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Prothyroliberin (TRH) ELISA Kit for Human

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS289526

MBS289526 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Prothyroliberin (TRH) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or… More details

$405 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Prothyroliberin (TRH), ELISA Kit
Full Product Name
Human Prothyroliberin ELISA Kit
Product Gene Name
TRH elisa kit
Product Synonym Names
Prothyroliberin; TRH; Pro-TRH; Prothyroliberin
Species Reactivity
Human
Assay Type
Sandwich
Detection Range
78-5000 pg/mL
Sensitivity
39 pg/mL
Preparation and Storage
For long term storage, please store the entire kit at -20 degree C.
Molecular Weight
27,404 Da
OMIM
613879
3D Structure
ModBase 3D Structure for P20396
Intra-Assay CV
<=8.6%
Inter-Assay CV
<=10.3%
Recovery
106%

Typical Testing Data/Standard Curve (for reference only) of TRH elisa kit

Human TRH ELISA Kit – Cat# MBS289526

Other Notes

Small volumes of TRH elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TRH. It may not necessarily be applicable to this product.

NCBI GI #
6005920
NCBI GeneID
7200
NCBI Accession #
NP_009048.1
UniProt Primary Accession #
P20396
UniProt Secondary Accession #
Q2TB83; B2R8R1
UniProt Related Accession #
P20396
GenBank Nucleotide #
NM_007117.4
NCBI Official Full Name
thyrotropin releasing hormone preproprotein
NCBI Official Synonym Full Names
thyrotropin releasing hormone
NCBI Official Symbol
TRH
NCBI Official Synonym Symbols
TRF; Pro-TRH
UniProt Protein Name
Pro-thyrotropin-releasing hormone
UniProt Synonym Protein Names
Prothyroliberin
Protein Family
Pro-thyrotropin-releasing hormone
UniProt Gene Name
TRH
UniProt Synonym Gene Names
Pro-TRH; TRH; TRF
UniProt Entry Name
TRH_HUMAN
NCBI Protein Information
thyrotropin releasing hormone

NCBI Summary for TRH

This gene encodes a member of the thyrotropin-releasing hormone family. Cleavage of the encoded proprotein releases mature thyrotropin-releasing hormone, which is a tripeptide hypothalamic regulatory hormone. The human proprotein contains six thyrotropin-releasing hormone tripeptides. Thyrotropin-releasing hormone is involved in the regulation and release of thyroid-stimulating hormone, as well as prolactin. Deficiency of this hormone has been associated with hypothalamic hypothyroidism. [provided by RefSeq, May 2013]
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UniProt Comments for TRH

TRH: Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. May promote hair shaft elongation, prolonge the hair cycle growth phase (anagen) and antagonized its termination by TGFB2. May also increase proliferation and inhibited apoptosis of hair matrix keratinocytes. Belongs to the TRH family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 3q13.3-q21

Cellular Component: extracellular region; nucleus; plasma membrane; secretory granule

Molecular Function: neuropeptide hormone activity; thyrotropin-releasing hormone activity

Biological Process: adult walking behavior; cell-cell signaling; eating behavior; histamine metabolic process; hormone-mediated signaling; negative regulation of glutamate secretion; positive regulation of gamma-aminobutyric acid secretion; positive regulation of insulin secretion; response to cold; response to corticosterone stimulus; response to ethanol; response to glucose stimulus; response to hypoxia; signal transduction

Disease: Thyrotropin-releasing Hormone Deficiency
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Research Articles on TRH

1. TRH rs13097335 may have a protective role toward the development of breast cancer.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with TRH elisa kit

 Reference Product  PubMed Publications
 PRL elisa kit  >1761 publications with TRH and PRL
 CCK elisa kit  >65 publications with TRH and CCK
 TRHR elisa kit  >54 publications with TRH and TRHR
 NTS elisa kit  >17 publications with TRH and NTS
 GRP elisa kit  >8 publications with TRH and GRP
 OXT elisa kit  >6 publications with TRH and OXT
 NPS elisa kit  >2 publications with TRH and NPS
 GNRH1 elisa kit  >1 publications with TRH and GNRH1

Pathways associated with TRH elisa kit

 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
 Peptide Ligand-binding Receptors Pathway antibodies  Peptide Ligand-binding Receptors Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By GPCR Pathway antibodies  Signaling By GPCR Pathway Diagram
 Thyroxine (Thyroid Hormone) Production Pathway antibodies  Thyroxine (Thyroid Hormone) Production Pathway Diagram

Diseases associated with TRH elisa kit

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >2018 publications with TRH and Nervous System Diseases
 Brain Diseases Antibodies  >1701 publications with TRH and Brain Diseases
 Depressive Disorder Antibodies  >337 publications with TRH and Depressive Disorder
 THYROTROPIN-RELEASING HORMONE DEFICIENCY Antibodies  >296 publications with TRH and THYROTROPIN-RELEASING HORMONE DEFICIENCY
 Kidney Diseases Antibodies  >162 publications with TRH and Kidney Diseases
 Disease Models, Animal Antibodies  >136 publications with TRH and Disease Models, Animal
 Hypertension Antibodies  >121 publications with TRH and Hypertension
 Seizures Antibodies  >94 publications with TRH and Seizures
 Hypothermia Antibodies  >93 publications with TRH and Hypothermia
 Weight Loss Antibodies  >92 publications with TRH and Weight Loss

Organs/Tissues associated with TRH elisa kit

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >4718 publications with TRH and Brain
 Testis Antibodies  >105 publications with TRH and Testis
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