• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Pannexin-1 (PANX1) ELISA Kit for Human

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS289634

MBS289634 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Pannexin-1 (PANX1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive… More details

$405 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Pannexin-1 (PANX1), ELISA Kit
Full Product Name
Human Pannexin-1 ELISA Kit
Product Gene Name
PANX1 elisa kit
Product Synonym Names
Pannexin-1; PANX1; MRS1; UNQ2529/PRO6028
Species Reactivity
Human
Assay Type
Sandwich
Detection Range
0.156-10 ng/mL
Sensitivity
0.078ng/ml
Preparation and Storage
For long term storage, please store the entire kit at -20 degree C.
Molecular Weight
47,635 Da
OMIM
608420
3D Structure
ModBase 3D Structure for Q96RD7
Intra-Assay CV
<=4.6%
Inter-Assay CV
<=8.3%
Recovery
83%

Typical Testing Data/Standard Curve (for reference only) of PANX1 elisa kit

Human PANX1 ELISA Kit – Cat# MBS289634

Other Notes

Small volumes of PANX1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PANX1. It may not necessarily be applicable to this product.

NCBI GI #
39995064
NCBI GeneID
24145
NCBI Accession #
NP_056183.2
UniProt Primary Accession #
Q96RD7
UniProt Secondary Accession #
O75968; Q543A0; Q6UW26; Q96AM9; Q96L77; Q96RS5
UniProt Related Accession #
Q96RD7
GenBank Nucleotide #
NM_015368.3
NCBI Official Full Name
pannexin-1
NCBI Official Synonym Full Names
pannexin 1
NCBI Official Symbol
PANX1
NCBI Official Synonym Symbols
PX1; MRS1; UNQ2529
UniProt Protein Name
Pannexin-1
Protein Family
Pannexin
UniProt Gene Name
PANX1
UniProt Synonym Gene Names
MRS1
UniProt Entry Name
PANX1_HUMAN
NCBI Protein Information
pannexin-1

NCBI Summary for PANX1

The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 2 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 2 may form cell type-specific gap junctions with distinct properties. [provided by RefSeq, Jul 2008]
Show more

UniProt Comments for PANX1

PANX1: Structural component of the gap junctions and the hemichannels. May play a role as a Ca(2+)-leak channel to regulate ER Ca(2+) homeostasis. Belongs to the pannexin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell adhesion; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 11q21

Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; gap junction; integral to membrane; membrane; plasma membrane; protein complex

Molecular Function: actin filament binding; calcium channel activity; gap junction hemi-channel activity; leak channel activity; protease binding; protein heterodimerization activity; receptor binding

Biological Process: calcium ion transport; cation transport; cell-cell signaling; innate immune response; positive regulation of interleukin-1 alpha secretion; positive regulation of interleukin-1 beta secretion; response to ATP; synaptic transmission
Show more

Research Articles on PANX1

1. Within this review, the regulation of Panx1 channels is discussed, with a focus on how they may contribute to platelet function.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with PANX1 elisa kit

 Reference Product  PubMed Publications
 PANX2 elisa kit  >41 publications with PANX1 and PANX2
 CASP1 elisa kit  >19 publications with PANX1 and CASP1
 P2RX7 elisa kit  >16 publications with PANX1 and P2RX7
 NLRP3 elisa kit  >6 publications with PANX1 and NLRP3
 CASP7 elisa kit  >4 publications with PANX1 and CASP7
 SUGT1 elisa kit  >1 publications with PANX1 and SUGT1

Pathways associated with PANX1 elisa kit

 Products by Pathway  Pathway Diagram
 Electric Transmission Across Gap Junctions Pathway antibodies  Electric Transmission Across Gap Junctions Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Inflammasomes Pathway antibodies  Inflammasomes Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 Neuronal System Pathway antibodies  Neuronal System Pathway Diagram
 Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor (NLR) Signaling Pathways antibodies  Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor (NLR) Signaling Pathways Diagram
 The NLRP3 Inflammasome Pathway antibodies  The NLRP3 Inflammasome Pathway Diagram
 Transmission Across Electrical Synapses Pathway antibodies  Transmission Across Electrical Synapses Pathway Diagram

Diseases associated with PANX1 elisa kit

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >41 publications with PANX1 and Inflammation
 Disease Models, Animal Antibodies  >17 publications with PANX1 and Disease Models, Animal
 Cardiovascular Diseases Antibodies  >12 publications with PANX1 and Cardiovascular Diseases
 Pain Antibodies  >9 publications with PANX1 and Pain
 Necrosis Antibodies  >8 publications with PANX1 and Necrosis
 Fibrosis Antibodies  >7 publications with PANX1 and Fibrosis
 Nerve Degeneration Antibodies  >6 publications with PANX1 and Nerve Degeneration
 Lung Diseases Antibodies  >4 publications with PANX1 and Lung Diseases
 Hypersensitivity Antibodies  >4 publications with PANX1 and Hypersensitivity
 Fatty Liver Antibodies  >3 publications with PANX1 and Fatty Liver

Organs/Tissues associated with PANX1 elisa kit

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >92 publications with PANX1 and Brain
 Muscle Antibodies  >29 publications with PANX1 and Muscle
 Eye Antibodies  >24 publications with PANX1 and Eye
 Vascular Antibodies  >20 publications with PANX1 and Vascular
 Embryonic Tissue Antibodies  >15 publications with PANX1 and Embryonic Tissue
 Skin Antibodies  >10 publications with PANX1 and Skin
 Kidney Antibodies  >8 publications with PANX1 and Kidney
 Lung Antibodies  >7 publications with PANX1 and Lung
 Liver Antibodies  >6 publications with PANX1 and Liver
 Bone Antibodies  >6 publications with PANX1 and Bone
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000