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Filamin-B (FLNB) ELISA Kit for Mouse

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS289766

MBS289766 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Filamin-B (Flnb) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive… More details

$405 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Filamin-B (Flnb), ELISA Kit
Full Product Name
Mouse Filamin-B ELISA Kit
Product Gene Name
Flnb elisa kit
Product Synonym Names
Filamin-B; FLN-B; ABP-280-like protein; Actin-binding-like protein; Beta-filamin; Flnb
Species Reactivity
Mouse
Assay Type
Sandwich
Detection Range
1.56-100 ng/mL
Sensitivity
0.79 ng/mL
Preparation and Storage
For long term storage, please store the entire kit at -20 degree C.
Molecular Weight
277,825 Da
3D Structure
ModBase 3D Structure for Q80X90
Intra-Assay CV
<=6.8%
Inter-Assay CV
<=8.9%
Recovery
83%

Typical Testing Data/Standard Curve (for reference only) of Flnb elisa kit

Mouse FLNB ELISA Kit – Cat# MBS289766

Other Notes

Small volumes of Flnb elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Flnb. It may not necessarily be applicable to this product.

NCBI GI #
594140560
NCBI GeneID
286940
NCBI Accession #
NP_001074896.1
UniProt Primary Accession #
Q80X90
UniProt Secondary Accession #
Q8VHX4; Q8VHX7; Q99KY3; E9QNV9
UniProt Related Accession #
Q80X90
GenBank Nucleotide #
NM_001081427.1
NCBI Official Full Name
filamin-B isoform a
NCBI Official Synonym Full Names
filamin, beta
NCBI Official Symbol
Flnb
NCBI Official Synonym Symbols
Fln-b; AL024016
UniProt Protein Name
Filamin-B
UniProt Synonym Protein Names
ABP-280-like protein; Actin-binding-like protein; Beta-filamin
Protein Family
Filamin
UniProt Gene Name
Flnb
UniProt Synonym Gene Names
FLN-B
UniProt Entry Name
FLNB_MOUSE
NCBI Protein Information
filamin-B

UniProt Comments for Flnb

FLNB: a ubiquitous cytoskeletal protein that links actin filaments to membrane glycoproteins. Six alternatively spliced isoforms have been described. Various interactions and localizations of isoforms affect myotube morphology and myogenesis. Isoforms 1 and 2 are expressed in placenta, bone marrow, brain, umbilical vein endothelial cells, retina and skeletal muscle. Isoform 1 is predominantly expressed in prostate, uterus, liver, thyroid, stomach, lymph node, small intestine, spleen, skeletal muscle, kidney, placenta, pancreas, heart, lung, platelets, endothelial cells, megakaryocytic and erythroleukemic cell lines. Isoform 2 is predominantly expressed in spinal cord and platelets. Also expressed in thyroid adenoma, neurofibrillary tangles (NFT), senile plaques in the hippocampus and cerebral cortex in Alzheimer's disease. Isoform 3 and isoform 6 are expressed predominantly in lung, heart, skeletal muscle, testis, spleen, thymus and leukocytes. Isoform 4 and isoform 5 are expressed in heart.

Protein type: Motility/polarity/chemotaxis; Actin-binding

Cellular Component: brush border; cytoplasm; cytoskeleton; focal adhesion; plasma membrane; stress fiber

Molecular Function: actin binding; identical protein binding; protein binding

Biological Process: actin cytoskeleton organization and biogenesis; cell differentiation; skeletal muscle development
Show more

Research Articles on Flnb

1. Fmn1 and FlnB have shared and independent functions.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Flnb elisa kit

 Products by Pathway  Pathway Diagram
 Antiviral Mechanism By IFN-stimulated Genes Pathway antibodies  Antiviral Mechanism By IFN-stimulated Genes Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 ISG15 Antiviral Mechanism Pathway antibodies  ISG15 Antiviral Mechanism Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Interferon Signaling Pathway antibodies  Interferon Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 Proteoglycans In Cancer Pathway antibodies  Proteoglycans In Cancer Pathway Diagram

Diseases associated with Flnb elisa kit

 Disease Name  Pubmed Publications
 Congenital Abnormalities Antibodies  >21 publications with Flnb and Congenital Abnormalities
 Spondylocarpotarsal synostosis Antibodies  >7 publications with Flnb and Spondylocarpotarsal synostosis
 Boomerang dysplasia Antibodies  >6 publications with Flnb and Boomerang dysplasia
 Nervous System Diseases Antibodies  >5 publications with Flnb and Nervous System Diseases
 Liver Diseases Antibodies  >3 publications with Flnb and Liver Diseases
 Liver Neoplasms Antibodies  >3 publications with Flnb and Liver Neoplasms
 Adenocarcinoma Antibodies  >3 publications with Flnb and Adenocarcinoma
 Carcinoma, Hepatocellular Antibodies  >3 publications with Flnb and Carcinoma, Hepatocellular
 ATELOSTEOGENESIS, TYPE III Antibodies  >3 publications with Flnb and ATELOSTEOGENESIS, TYPE III
 Cardiovascular Diseases Antibodies  >2 publications with Flnb and Cardiovascular Diseases

Organs/Tissues associated with Flnb elisa kit

 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >21 publications with Flnb and Bone
 Connective Tissue Antibodies  >7 publications with Flnb and Connective Tissue
 Heart Antibodies  >4 publications with Flnb and Heart
 Brain Antibodies  >4 publications with Flnb and Brain
 Liver Antibodies  >3 publications with Flnb and Liver
 Muscle Antibodies  >3 publications with Flnb and Muscle
 Bone Marrow Antibodies  >2 publications with Flnb and Bone Marrow
 Lung Antibodies  >2 publications with Flnb and Lung
 Embryonic Tissue Antibodies  >2 publications with Flnb and Embryonic Tissue
 Spleen Antibodies  >1 publications with Flnb and Spleen
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