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NDUFA4 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2524064

The protein encoded by this gene belongs to the complex I 9kDa subunit family. Mammalian complex I of mitochondrial respiratory chain is composed of 45 different subunits. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
NDUFA4, Polyclonal Antibody
Full Product Name
NDUFA4 Polyclonal Antibody
Product Gene Name
anti-NDUFA4 antibody
Product Synonym Names
MLRQ; CI-9k; CI-MLRQ
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen affinity purification
Concentration
2.7mg/mL (lot specific)
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
Molecular Weight
9,370 Da
OMIM
256000
3D Structure
ModBase 3D Structure for O00483
Immunogen
Synthetic peptide of human NDUFA4
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-NDUFA4 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-NDUFA4 antibody
WB: 1:500-1:2000
IHC: 1:50-1:200

Western Blot (WB) of anti-NDUFA4 antibody

Western Blot analysis of SKOV3 cell and Human fetal liver tissue, Human fetal brain tissue and Hela cell using NDUFA4 Polyclonal Antibody at dilution of 1:300
Rabbit Anti-NDUFA4 Polyclonal Antibody – Cat# MBS2524064

Immunohistochemistry (IHC) of anti-NDUFA4 antibody

Immunohistochemistry of paraffin-embedded Human colon cancer using NDUFA4 Polyclonal Antibody at dilution of 1:40
Rabbit Anti-NDUFA4 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2524064

Immunohistochemistry (IHC) of anti-NDUFA4 antibody

Immunohistochemistry of paraffin-embedded Human liver cancer using NDUFA4 Polyclonal Antibody at dilution of 1:40
Rabbit Anti-NDUFA4 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2524064

Other Notes

Small volumes of anti-NDUFA4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NDUFA4 purchase

MBS2524064 is an antibody targeting NDUFA4. Also known as NDUFA4 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for NDUFA4. It may not necessarily be applicable to this product.

NCBI GI #
49456393
NCBI GeneID
4697
NCBI Accession #
CAG46517.1
UniProt Primary Accession #
O00483
UniProt Secondary Accession #
Q6FHN5; A4D109
UniProt Related Accession #
O00483
NCBI Official Full Name
NDUFA4
NCBI Official Synonym Full Names
NDUFA4, mitochondrial complex associated
NCBI Official Symbol
NDUFA4
NCBI Official Synonym Symbols
MLRQ; CI-9k; CI-MLRQ
UniProt Protein Name
Cytochrome c oxidase subunit NDUFA4
UniProt Synonym Protein Names
Complex I-MLRQ; CI-MLRQ; NADH-ubiquinone oxidoreductase MLRQ subunit
Protein Family
Cytochrome c oxidase
UniProt Gene Name
NDUFA4
UniProt Synonym Gene Names
CI-MLRQ
UniProt Entry Name
NDUA4_HUMAN
NCBI Protein Information
cytochrome c oxidase subunit NDUFA4; Complex I 9kDa subunit; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4; NADH-ubiquinone oxidoreductase MLRQ subunit; complex I-MLRQ

UniProt Comments for NDUFA4

NDUFA4: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Belongs to the complex I NDUFA4 subunit family.

Protein type: Energy Metabolism - oxidative phosphorylation; EC 1.6.99.3; Oxidoreductase; Mitochondrial; EC 1.6.5.3

Chromosomal Location of Human Ortholog: 7p21.3

Cellular Component: mitochondrion; mitochondrial inner membrane; mitochondrial respiratory chain complex IV; mitochondrial respiratory chain complex I

Molecular Function: cytochrome-c oxidase activity; protein binding; NADH dehydrogenase (ubiquinone) activity; protein complex binding

Biological Process: cellular metabolic process; mitochondrial electron transport, NADH to ubiquinone
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Research Articles on NDUFA4

1. Findings support reassignment of the NDUFA4 protein to complex IV and suggest that patients with unexplained COX deficiency should be screened for NDUFA4 mutations.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-NDUFA4 antibody

 Reference Product  PubMed Publications
 NDUFA1 antibody  >2 publications with NDUFA4 and NDUFA1

Pathways associated with anti-NDUFA4 antibody

 Products by Pathway  Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Electron Transport Chain Pathway antibodies  Electron Transport Chain Pathway Diagram
 Huntington's Disease Pathway antibodies  Huntington's Disease Pathway Diagram
 Huntington's Disease Pathway antibodies  Huntington's Disease Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 NADH Dehydrogenase (ubiquinone) 1 Alpha Subcomplex Pathway antibodies  NADH Dehydrogenase (ubiquinone) 1 Alpha Subcomplex Pathway Diagram
 NADH Dehydrogenase (ubiquinone) 1 Alpha Subcomplex Pathway antibodies  NADH Dehydrogenase (ubiquinone) 1 Alpha Subcomplex Pathway Diagram
 Non-alcoholic Fatty Liver Disease (NAFLD) Pathway antibodies  Non-alcoholic Fatty Liver Disease (NAFLD) Pathway Diagram

Diseases associated with anti-NDUFA4 antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >6 publications with NDUFA4 and Nervous System Diseases
 Death Antibodies  >2 publications with NDUFA4 and Death
 Cognition Disorders Antibodies  >1 publications with NDUFA4 and Cognition Disorders
 Mitochondrial Diseases Antibodies  >1 publications with NDUFA4 and Mitochondrial Diseases

Organs/Tissues associated with anti-NDUFA4 antibody

 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >1 publications with NDUFA4 and Kidney
 Muscle Antibodies  >1 publications with NDUFA4 and Muscle
 Liver Antibodies  >1 publications with NDUFA4 and Liver
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