Rabbit Anti-STAG3 Antibody – Cat# MBS000003

STAG3 Antibody – Rabbit

Name: STAG3 Antibody; Rabbit; Human-Reactive; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS000003
Price: 595 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS000003

MBS000003 is an antibody targeting STAG3. Also known as Rabbit STAG3 Antibody. Reactive in Human. Host: Rabbit. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

STAG3, Antibody

Full Product Name

Rabbit STAG3 Antibody

Product Gene Name

anti-STAG3 antibody

Host

Rabbit

Species Reactivity

Human

Form/Format

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol

Concentration

1 mg/ml (lot specific)

Molecular Weight

139,034 Da

Chromosome Location

Chromosome: 7; NC_000007.13 (99775538..99812010). Location: 7q22.1

OMIM

608489

3D Structure

ModBase 3D Structure for Q9UJ98

Applications Tested/Suitable for anti-STAG3 antibody

ELISA (EIA), Western Blot (WB)

Other Notes

Small volumes of anti-STAG3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for STAG3. It may not necessarily be applicable to this product.

NCBI GI #

57863310

NCBI GeneID

10734

NCBI Accession #

NP_036579.2

UniProt Primary Accession #

Q9UJ98

UniProt Secondary Accession #

Q8NDP3; A6H8Z1; D6W5U8

UniProt Related Accession #

Q9UJ98

GenBank Nucleotide #

NM_012447.2

NCBI Official Full Name

cohesin subunit SA-3

NCBI Official Synonym Full Names

stromal antigen 3

NCBI Official Symbol

STAG3

UniProt Protein Name

Cohesin subunit SA-3

UniProt Synonym Protein Names

SCC3 homolog 3; Stromal antigen 3; Stromalin-3

Protein Family

Cofilin

UniProt Gene Name

STAG3

UniProt Entry Name

STAG3_HUMAN

NCBI Protein Information

cohesin subunit SA-3; stromalin 3; stromalin-3; SCC3 homolog 3

NCBI Summary for STAG3

The protein encoded by this gene is expressed in the nucleus and is a subunit of the cohesin complex which regulates the cohesion of sister chromatids during cell division. A mutation in this gene is associated with premature ovarian failure. Alternate splicing results in multiple transcript variants encoding distinct isoforms. This gene has multiple pseudogenes. [provided by RefSeq, Apr 2014]

UniProt Comments for STAG3

STAG3: Meiosis specific component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis- specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I. Belongs to the SCC3 family. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 7q22.1

Cellular Component: extracellular space; nucleolus; synaptonemal complex; nucleus; chromosome, pericentric region

Biological Process: synaptonemal complex assembly

Disease: Premature Ovarian Failure 8

Research Articles on STAG3

1. we show evidence for the involvement of a common allele of STAG3 in the development of epithelial ovarian cancer

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-STAG3 antibody

Products by Pathway	Pathway Diagram
Cell Cycle Pathway antibodies	Cell Cycle Pathway Diagram
Chromosome Maintenance Pathway antibodies	Chromosome Maintenance Pathway Diagram
Meiosis Pathway antibodies	Meiosis Pathway Diagram
Meiotic Synapsis Pathway antibodies	Meiotic Synapsis Pathway Diagram
Oocyte Meiosis Pathway antibodies	Oocyte Meiosis Pathway Diagram
Oocyte Meiosis Pathway antibodies	Oocyte Meiosis Pathway Diagram

Diseases associated with anti-STAG3 antibody

Disease Name	Pubmed Publications
Immune System Diseases Antibodies	>1 publications with STAG3 and Immune System Diseases
Heart Diseases Antibodies	>1 publications with STAG3 and Heart Diseases
Infertility, Female Antibodies	>1 publications with STAG3 and Infertility, Female
Congenital Abnormalities Antibodies	>1 publications with STAG3 and Congenital Abnormalities

Organs/Tissues associated with anti-STAG3 antibody

Organ/Tissue Name	Pubmed Publications
Testis Antibodies	>10 publications with STAG3 and Testis