Transforming Growth Factor Beta Stimulated (TSC22) ELISA Kit for Cavy

Name: Cavy TSC22 ELISA Kit; Transforming Growth Factor Beta Stimulated; MyBioSource
Brand: MyBioSource
SKU: MBS030031
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS030031

MBS030031 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Transforming Growth Factor Beta Stimulated Protein Clone 22 (TSC22) ELISA Kit target analytes in biological samples. The… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Transforming Growth Factor Beta Stimulated Protein Clone 22 (TSC22), ELISA Kit

Full Product Name

Cavy Transforming Growth Factor Beta Stimulated Protein Clone 22 ELISA Kit

Product Gene Name

TSC22 elisa kit

Species Reactivity

Cavy

Assay Type

Sandwich

Preparation and Storage

Store all reagents at 2-8 degree C

Molecular Weight

109,677 Da

OMIM

607715

3D Structure

ModBase 3D Structure for Q15714

Other Notes

Small volumes of TSC22 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TSC22. It may not necessarily be applicable to this product.

NCBI GI #

345090984

NCBI GeneID

8848

NCBI Accession #

NP_001230727.1

UniProt Primary Accession #

Q15714

UniProt Secondary Accession #

O00666; Q6AHX5; Q6IBU1; Q8NCN1; Q96JS5; B3KRL7; B9EGI0

UniProt Related Accession #

Q15714

GenBank Nucleotide #

NM_001243798.1

NCBI Official Full Name

TSC22 domain family protein 1 isoform 3

NCBI Official Synonym Full Names

TSC22 domain family, member 1

NCBI Official Symbol

TSC22D1

NCBI Official Synonym Symbols

Ptg-2; TSC22; TGFB1I4

UniProt Protein Name

TSC22 domain family protein 1

UniProt Synonym Protein Names

Cerebral protein 2; Regulatory protein TSC-22; TGFB-stimulated clone 22 homolog; Transforming growth factor beta-1-induced transcript 4 protein

UniProt Gene Name

TSC22D1

UniProt Synonym Gene Names

KIAA1994; TGFB1I4; TSC22

UniProt Entry Name

T22D1_HUMAN

NCBI Protein Information

TSC22 domain family protein 1; cerebral protein 2; regulatory protein TSC-22; TGFbeta-stimulated clone 22; TGFB-stimulated clone 22 homolog; transcriptional regulator TSC-22; transforming growth factor beta-stimulated protein TSC-22; transforming growth factor beta-1-induced transcript 4 protein

NCBI Summary for TSC22

This gene encodes a member of the TSC22 domain family of leucine zipper transcription factors. The encoded protein is stimulated by transforming growth factor beta, and regulates the transcription of multiple genes including C-type natriuretic peptide. The encoded protein may play a critical role in tumor suppression through the induction of cancer cell apoptosis, and a single nucleotide polymorphism in the promoter of this gene has been associated with diabetic nephropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]

UniProt Comments for TSC22

TSC22D1: Transcriptional repressor. Acts on the C-type natriuretic peptide (CNP) promoter. Belongs to the TSC-22/Dip/Bun family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 13q14

Cellular Component: cytoplasm; nucleus

Molecular Function: protein binding; transcription factor activity

Biological Process: transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; positive regulation of apoptosis; positive regulation of cell proliferation; negative regulation of apoptosis

Research Articles on TSC22

1. TSC-22 acts as a tumor suppressor by safeguarding p53 from poly-ubiquitination mediated-degradation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with TSC22 elisa kit

Reference Product	PubMed Publications
TSC22D4 elisa kit	>2 publications with TSC22 and TSC22D4

Diseases associated with TSC22 elisa kit

Disease Name	Pubmed Publications
Neoplasms Antibodies	>21 publications with TSC22 and Neoplasms
Carcinoma Antibodies	>3 publications with TSC22 and Carcinoma
Cell Transformation, Neoplastic Antibodies	>3 publications with TSC22 and Cell Transformation, Neoplastic
Neoplasms, Experimental Antibodies	>2 publications with TSC22 and Neoplasms, Experimental
Cardiovascular Diseases Antibodies	>2 publications with TSC22 and Cardiovascular Diseases
Disease Models, Animal Antibodies	>1 publications with TSC22 and Disease Models, Animal
Liver Diseases Antibodies	>1 publications with TSC22 and Liver Diseases
Lung Neoplasms Antibodies	>1 publications with TSC22 and Lung Neoplasms
Kidney Diseases Antibodies	>1 publications with TSC22 and Kidney Diseases
Liver Neoplasms Antibodies	>1 publications with TSC22 and Liver Neoplasms

Organs/Tissues associated with TSC22 elisa kit

Organ/Tissue Name	Pubmed Publications
Salivary Gland Antibodies	>10 publications with TSC22 and Salivary Gland
Brain Antibodies	>7 publications with TSC22 and Brain
Vascular Antibodies	>4 publications with TSC22 and Vascular
Heart Antibodies	>3 publications with TSC22 and Heart
Prostate Antibodies	>3 publications with TSC22 and Prostate
Blood Antibodies	>3 publications with TSC22 and Blood
Muscle Antibodies	>3 publications with TSC22 and Muscle
Kidney Antibodies	>2 publications with TSC22 and Kidney
Liver Antibodies	>2 publications with TSC22 and Liver
Lung Antibodies	>2 publications with TSC22 and Lung