Mouse Anti-CD8 Monoclonal Antibody – Cat# MBS3030003

CD8 Antibody – Mouse Monoclonal

Name: CD8 Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS3030003
Price: 275 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3030003

Anti-CD8 may be used in studies of immunoregulation and T-lymphocyte mediated suppression, autoimmune disorders, immunodeficiency states and acute lymphoblastic leukemia and lymphoma. More details

$275 / 1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CD8, Monoclonal Antibody

Full Product Name

anti-Human CD8 antibody (UCHT-4)

Product Gene Name

anti-CD8 antibody

Clonality

Monoclonal

Isotype

Mouse IgG2a

Clone Number

UCHT-4

Host

Mouse

Species Reactivity

Human

Form/Format

0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.

Purity/Purification

>95% by SDS-PAGE and HPLC
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Concentration

1.0-5.0mg/ml (lot specific)

Specificity

Anti-CD8 In Vivo Antibody - Low Endotoxin (UCHT-4) recognizes Human CD8. Anti-Human CD8 recognizes a T-cell glycoprotein cell surface complex (Mr 32 kDa) which defines the cytotoxic/suppressor population of mature T-lymphocytes. The CD8 complex interacts with class I MHC molecules resulting in increased adhesion between CD8+ T-lymphocytes and their target cells. Binding of the CD8 antigen to Class I MHC molecules enhances T-cell activation. The cytoplasmic portion of the CD8 antigen is associated with a protein tyrosine kinase (p56lck).

Preparation and Storage

anti-CD8 In Vivo Antibody - Low Endotoxin (UCHT-4) is stable for at least one week when stored sterile at 2-8 degree C. For long term storage aseptically aliquot in working volumes without diluting and store at -80 degree C. Avoid Repeated Freeze Thaw Cycles.

Matching Pairs

Antibody: CD8 Clone #UCHT-4 (MBS3030003)
Isotype Control: KLH Clone #C1.18.4 (MBS3030260)

GMP

Manufactured according to cGMP (Current Good Manufacturing Practice) standards.

Endotoxin

<1.0 EU/mg as determined by the LAL method

Aggregation

Aggregation level <= 5%

Antigen Distribution

The CD8 antigen is expressed on approximately 19-48% of normal human peripheral blood lymphocytes and > 90% of normal thymocytes. It is also present on a subset of NK cells. Subjects infected with HIV have been shown to exhibit increased levels of CD8+ lymphocytes with a continual decrease in CD4+ lymphocytes.

Product Categories/Family for anti-CD8 antibody

Low Endotoxin; anti-human

Applications Tested/Suitable for anti-CD8 antibody

Flow Cytometry (FC/FACS), Western Blot (WB), Immunoprecipitation (IP), Functional Assay (FUNC), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)

Other Notes

Small volumes of anti-CD8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD8 purchase

MBS3030003 is an antibody targeting CD8. Also known as anti-Human CD8 antibody (UCHT-4). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CD8. It may not necessarily be applicable to this product.

Protein Family

CD81 antigen

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.