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CD62L Antibody – Rat Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3030071

CD62L is a 74-95 kD glycoprotein also known as L-selectin, LECAM-1, Ly-22, and LAM-1. It is a member of the selectin family and is expressed on the majority of B and naïve T cells, a subset of memory T cells, monocytes, granulocytes, most thymocytes, and a… More details

$275 / 1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD62L, Monoclonal Antibody
Full Product Name
Anti-Mouse CD62L In Vivo Antibody - Low Endotoxin (MEL-14)
Product Gene Name
Product Synonym Names
L-selectin; Sell; Leukocyte adhesion molecule 1; LAM-1; Leukocyte-endothelial cell adhesion molecule 1; LECAM1Lymph node homing receptor1; Lymphocyte antigen 221;Ly-221; Lymphocyte surface MEL-14 antigen; Lnhr; Ly-22; Ly22
Clonality
Monoclonal
Isotype
Rat IgG2a
Clone Number
MEL-14
Host
Rat
Species Reactivity
Mouse
Form/Format
0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Purity/Purification
>95% by SDS-PAGE and HPLC
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Concentration
1.0-5.0mg/ml (lot specific)
Specificity
Anti-CD62L In Vivo Antibody - Low Endotoxin (MEL-14) recognizes an epitope on Mouse CD62L
Preparation and Storage
anti-CD62L In Vivo Antibody - Low Endotoxin (MEL-14) is stable for at least six (6) weeks when stored sterile at 2-8 degree C. For long-term storage aseptically aliquot in working volumes without diluting and store at -80 degree C. Avoid Repeated Freeze Thaw Cycles.
Molecular Weight
42,288 Da
3D Structure
ModBase 3D Structure for P18337
GMP
Manufactured according to cGMP (Current Good Manufacturing Practice) standards.
Endotoxin
<= 1.0 EU/mg as determined by the LAL method
Immunogen
C3H/eb mouse B lymphoma 38C-13
Aggregation
Aggregation level <= 5%
Antigen Distribution
Subsets of B and T cells, monocytes, granulocytes, subset of NK cells

Product Categories/Family for anti-CD62L antibody

Applications Tested/Suitable for anti-CD62L antibody
Immunoprecipitation (IP), Western Blot (WB), Blocking (BL), Flow Cytometry (FC/FACS), Immunohistochemistry-Frozen (IHC-F), Mass Cytometry (CyTOF)

Western Blot (WB) of anti-CD62L antibody

Rat Anti-CD62L Monoclonal Antibody – Cat# MBS3030071

Other Notes

Small volumes of anti-CD62L antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD62L purchase

MBS3030071 is an antibody targeting CD62L. Also known as Anti-Mouse CD62L In Vivo Antibody - Low Endotoxin (MEL-14). Reactive in Mouse. Host: Rat.

Additional Details

NCBI/Uniprot data below describe general gene information for CD62L. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
NCBI Official Full Name
L-selectin
NCBI Official Synonym Full Names
selectin, lymphocyte
NCBI Official Symbol
Sell
NCBI Official Synonym Symbols
Lnhr; CD62L; Ly-22; Lyam1; Ly-m22; Lyam-1; LECAM-1; AI528707; L-selectin
UniProt Protein Name
L-selectin
UniProt Synonym Protein Names
CD62 antigen-like family member L; Leukocyte adhesion molecule 1; LAM-1; Leukocyte-endothelial cell adhesion molecule 1; LECAM1; Lymph node homing receptor; Lymphocyte antigen 22; Ly-22; Lymphocyte surface MEL-14 antigen; CD_antigen: CD62L
Protein Family
UniProt Gene Name
Sell
UniProt Synonym Gene Names
Lnhr; Ly-22; Ly22; LAM-1; LECAM1; Ly-22
UniProt Entry Name
LYAM1_MOUSE
NCBI Protein Information
L-selectin; LAM-1; LECAM1; lymphocyte antigen 22; lymph node homing receptor; leukocyte adhesion molecule 1; CD62 antigen-like family member L; lymphocyte surface MEL-14 antigen; leukocyte-endothelial cell adhesion molecule 1

UniProt Comments for CD62L

SELL: Cell surface adhesion protein. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia. Belongs to the selectin/LECAM family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Cellular Component: cell surface; membrane; integral to membrane; plasma membrane; external side of plasma membrane

Molecular Function: protein binding; protease binding; cell adhesion molecule binding; carbohydrate binding; glycolipid binding

Biological Process: regulation of apoptosis; cell adhesion; response to ATP
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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