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PD-L2 Antibody – Rat Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3030150

MBS3030150 is an antibody targeting PD-L2. Also known as Anti-Mouse PD-L2 In Vivo Antibody - Ultra Low Endotoxin (TY25). Reactive in Mouse. Host: Rat. More details

$675 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PD-L2, Monoclonal Antibody
Full Product Name
Anti-Mouse PD-L2 In Vivo Antibody - Ultra Low Endotoxin (TY25)
Product Gene Name
Product Synonym Names
Programmed cell death 1 ligand 2; Pdcd1lg2; PD-1 ligand 2; PD-L2; PDCD1 ligand 2; Programmed death ligand 2; Butyrophilin B7-DC; B7-DC; B7dc; Btdc; Pdl2
Clonality
Monoclonal
Isotype
Rat IgG2a
Clone Number
TY25
Host
Rat
Species Reactivity
Mouse
Form/Format
0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Purity/Purification
>98% by SDS-PAGE and HPLC
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Concentration
1.0mg/ml (lot specific)
Specificity
Anti-PD-L2 In Vivo Antibody - Low Endotoxin (TY25) recognizes an epitope on Mouse B7-DC
Preparation and Storage
anti-PD-L2 In Vivo Antibody - Low Endotoxin (TY25) is stable for at least one week when stored sterile at 2-8 degree C. For long term storage aseptically aliquot in working volumes without diluting and store at -80 degree C. Avoid Repeated Freeze Thaw Cycles.
Molecular Weight
27,820 Da
3D Structure
ModBase 3D Structure for Q9WUL5
GMP
Manufactured according to cGMP (Current Good Manufacturing Practice) standards.
Endotoxin
<= 0.75 EU/mg as determined by the LAL method
Immunogen
Purified transfected Mouse B7-DC cell line
Aggregation
Aggregation level <= 1%
IMPACT Pathogen Test
We use the IMPACT test generated by IDEXX Laboratories to guarantee our Ultra Low Endotoxin antibodies are pathogen free. Our rat antibodies are tested for: Mycoplasma spp Mycoplasma pulmonis Pneumonia virus of mice Kilham's rat virus Toolan's H1 virus Rat parvovirus Lymphocytic choriomeningitis virus Rat cytomegalovirus Sendai virus Rat coronavirus Sialodacryoadenitis virus Rat minute virus Seoul virus Mouse adenovirus Reovirus 3 Rat theilovirus

Product Categories/Family for anti-PD-L2 antibody

Applications Tested/Suitable for anti-PD-L2 antibody
Western Blot (WB), Blocking (BL), Flow Cytometry (FC/FACS), Immunohistochemistry-Frozen (IHC-F), Immunoprecipitation (IP)

Other Notes

Small volumes of anti-PD-L2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PD-L2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
programmed cell death 1 ligand 2
NCBI Official Synonym Full Names
programmed cell death 1 ligand 2
NCBI Official Symbol
Pdcd1lg2
NCBI Official Synonym Symbols
Btdc; B7-DC; PD-L2; F730015O22Rik
UniProt Protein Name
Programmed cell death 1 ligand 2
UniProt Synonym Protein Names
Butyrophilin B7-DC; B7-DC; CD_antigen: CD273
UniProt Gene Name
Pdcd1lg2
UniProt Synonym Gene Names
B7dc; Btdc; Cd273; Pdl2; PD-1 ligand 2; PD-L2; PDCD1 ligand 2; Programmed death ligand 2; B7-DC
UniProt Entry Name
PD1L2_MOUSE
NCBI Protein Information
programmed cell death 1 ligand 2; PD-1 ligand 2; PDCD1 ligand 2; butyrophilin B7-DC; butyrophilin-like protein; programmed death ligand 2

UniProt Comments for PD-L2

PDCD1LG2: Involved in the costimulatory signal, essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. Belongs to the immunoglobulin superfamily. BTN/MOG family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Receptor, misc.; Membrane protein, integral

Cellular Component: membrane; plasma membrane; integral to membrane

Molecular Function: protein binding

Biological Process: negative regulation of T cell proliferation; negative regulation of interleukin-10 production; negative regulation of activated T cell proliferation; negative regulation of interferon-gamma production; positive regulation of T cell proliferation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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