TCR Beta (TCRBeta) Antibody – Hamster Monoclonal

TCRbeta antibody, clone H57-597, recognizes the beta chain of the T cell receptor (TCRbeta), expressed on alphabeta thymocytes and T lymphocytes, as well as natural killer T (NKT) cells. TCRbeta is a transmembrane protein that consists of an amino-terminal variable region, a constant region, and a stalk segment covalently linked to the TCR alpha chain (TCRalpha) via a disulfide bond. TCRalpha/beta does not contain signaling domains and is instead noncovalently associated with the CD3 complex (TCR-CD3), essential for TCR signaling. TCRalpha/beta recognizes antigens bound to major histocompatibility complex (MHC) molecules, resulting in phosphorylation of CD3 ITAMs and subsequent T cell activation, proliferation, and survival.

Small volumes of anti-TCRBeta antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS3030156 is an antibody targeting TCRBeta. Also known as Anti-Mouse TCR beta In Vivo Antibody - Low Endotoxin (H57-597). Reactive in Mouse. Host: Armenian Hamster.