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Prostaglandin D Synthase (PGDS) ELISA Kit for Horse

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS031095

MBS031095 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Prostaglandin D Synthase (PGDS) ELISA Kit target analytes in biological samples. The concentration gradients of the kit… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Prostaglandin D Synthase (PGDS), ELISA Kit
Full Product Name
Horse Prostaglandin D Synthase ELISA Kit
Product Gene Name
PGDS elisa kit
Species Reactivity
Horse
Assay Type
Sandwich
Preparation and Storage
Store all reagents at 2-8 degree C
Molecular Weight
23,344 Da
Chromosome Location
Chromosome: 4; NC_000004.11 (95219707..95264027, complement). Location: 4q22.3
OMIM
602598
3D Structure
ModBase 3D Structure for O60760

Other Notes

Small volumes of PGDS elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PGDS. It may not necessarily be applicable to this product.

NCBI GI #
49456319
NCBI GeneID
27306
NCBI Accession #
CAG46480.1
UniProt Primary Accession #
O60760
UniProt Secondary Accession #
Q6FHT9
UniProt Related Accession #
O60760
NCBI Official Full Name
PGDS
NCBI Official Synonym Full Names
hematopoietic prostaglandin D synthase
NCBI Official Symbol
HPGDS
NCBI Official Synonym Symbols
GSTS; PGD2; PGDS; GSTS1-1
UniProt Protein Name
Hematopoietic prostaglandin D synthase
UniProt Synonym Protein Names
GST class-sigma; Glutathione S-transferase (EC:2.5.1.18); Glutathione-dependent PGD synthase; Glutathione-requiring prostaglandin D synthase; Prostaglandin-H2 D-isomerase
Protein Family
Gamma-DL-glutamyl hydrolase
UniProt Gene Name
HPGDS
UniProt Synonym Gene Names
GSTS; PGDS; PTGDS2; H-PGDS
UniProt Entry Name
HPGDS_HUMAN
NCBI Protein Information
hematopoietic prostaglandin D synthase; GST class-sigma; prostaglandin-H2 D-isomerase; glutathione S-transferase sigma; glutathione-dependent PGD synthase; glutathione-dependent PGD synthetase; hematopoietic prostaglandin D2 synthase; glutathione-requiring prostaglandin D synthase

NCBI Summary for PGDS

Prostaglandin-D synthase is a sigma class glutathione-S-transferase family member. The enzyme catalyzes the conversion of PGH2 to PGD2 and plays a role in the production of prostanoids in the immune system and mast cells. The presence of this enzyme can be used to identify the differentiation stage of human megakaryocytes. [provided by RefSeq, Jul 2008]
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UniProt Comments for PGDS

Ptgds2: Bifunctional enzyme which catalyzes both the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation, and the conjugation of glutathione with a wide range of aryl halides and organic isothiocyanates. Also exhibits low glutathione-peroxidase activity towards cumene hydroperoxide. Belongs to the GST superfamily. Sigma family.

Protein type: EC 2.5.1.18; EC 5.3.99.2; Lipid Metabolism - arachidonic acid; Isomerase

Chromosomal Location of Human Ortholog: 4q22.3

Cellular Component: cytoplasm; cytosol

Molecular Function: protein homodimerization activity; prostaglandin-D synthase activity; glutathione transferase activity; magnesium ion binding; calcium ion binding

Biological Process: xenobiotic metabolic process; cyclooxygenase pathway; arachidonic acid metabolic process; locomotory behavior; signal transduction; prostaglandin metabolic process
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Research Articles on PGDS

1. the Val187Ile HPGDS isoenzyme common among African Americans is not associated with colorectal cancer risk

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with PGDS elisa kit

 Reference Product  PubMed Publications
 PTGS2 elisa kit  >11 publications with PGDS and PTGS2
 PTGS1 elisa kit  >7 publications with PGDS and PTGS1
 PTGIS elisa kit  >1 publications with PGDS and PTGIS
 AKR1C3 elisa kit  >1 publications with PGDS and AKR1C3
 PTGDS elisa kit  >1 publications with PGDS and PTGDS
 PTGES2 elisa kit  >1 publications with PGDS and PTGES2
 TBXAS1 elisa kit  >1 publications with PGDS and TBXAS1
 PTGES elisa kit  >1 publications with PGDS and PTGES

Pathways associated with PGDS elisa kit

 Products by Pathway  Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Biological Oxidations Pathway antibodies  Biological Oxidations Pathway Diagram
 C20 Prostanoid Biosynthesis Pathway antibodies  C20 Prostanoid Biosynthesis Pathway Diagram
 Glutathione Conjugation Pathway antibodies  Glutathione Conjugation Pathway Diagram
 Integrated Pancreatic Cancer Pathway antibodies  Integrated Pancreatic Cancer Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Phase II Conjugation Pathway antibodies  Phase II Conjugation Pathway Diagram

Diseases associated with PGDS elisa kit

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >11 publications with PGDS and Inflammation
 Nervous System Diseases Antibodies  >6 publications with PGDS and Nervous System Diseases
 Neoplasms Antibodies  >6 publications with PGDS and Neoplasms
 Disease Models, Animal Antibodies  >5 publications with PGDS and Disease Models, Animal
 Necrosis Antibodies  >2 publications with PGDS and Necrosis
 Drug Toxicity Antibodies  >2 publications with PGDS and Drug Toxicity
 Cardiovascular Diseases Antibodies  >2 publications with PGDS and Cardiovascular Diseases
 Prenatal Exposure Delayed Effects Antibodies  >1 publications with PGDS and Prenatal Exposure Delayed Effects
 Neoplasms, Experimental Antibodies  >1 publications with PGDS and Neoplasms, Experimental
 Edema Antibodies  >1 publications with PGDS and Edema

Organs/Tissues associated with PGDS elisa kit

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >7 publications with PGDS and Blood
 Brain Antibodies  >6 publications with PGDS and Brain
 Connective Tissue Antibodies  >1 publications with PGDS and Connective Tissue
 Placenta Antibodies  >1 publications with PGDS and Placenta
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