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Defensin, Beta-1 (A.a. 1-36) (DEFB1) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS311954

MBS311954 is an antibody targeting DEFB1. Also known as MAb to beta-Defensin-1 (a.a. 1-36). Reactive in Human. Host: Mouse.Source: Cell Culture. More details

$540 / 0.01 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Defensin, beta-1 (a.a. 1-36) (DEFB1), Monoclonal Antibody
Full Product Name
MAb to beta-Defensin-1 (a.a. 1-36)
Product Gene Name
Product Synonym Names
Monoclonal Antibody to Human Defensin beta-1 (amino acids 1-36)
Clonality
Monoclonal
Isotype
IgG1
Host
Host: Mouse.
Source: Cell Culture
Species Reactivity
Human
Form/Format
Purified, Lyophilized
Reconstitute in 10ul double distilled water.
Purity/Purification
Protein A chromatography
Concentration
1mg/ml (prior to lyophilization) (lot specific)
Specificity
Defensin, beta-1 (a.a. 1-36)
Synthetic human beta-Defensin 1 (a.a. 1-36).
Preparation and Storage
Store lyophilized product at 2 to 8 degree C. After reconstitution, store at -20 degree C. Avoid multiple freeze/thaw cycles.
Molecular Weight
7,420 Da
Chromosome Location
Chromosome: 8; NC_000008.10 (6728097..6735529, complement). Location: 8p23.1
OMIM
602056
3D Structure
ModBase 3D Structure for P60022
Immunogen
Synthetic human beta-Defensin 1 (a.a. 1-36). (DHYNCVSSGGQCLYSACPIFTKIQGTCYRGKAKCCK)
Affinity Constant
Not determined.
Buffer
Lyophilized from 50mM Tris, pH 7.4
Preservative
No
Lyophilized
Yes
Important Note
Vial Contains Small Quantity. Centrifuge Product Before Opening!
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-DEFB1 antibody
EIA/ELISA, Western Blot

Product References and Citations for anti-DEFB1 antibody

• Zucht, H.D., et al., (1998), "Human beta-defensin-1: A urinary peptide present in variant molecular forms and its putative functional implication", Eur. J. Med. Res., 3:315-323.

Other Notes

Small volumes of anti-DEFB1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for DEFB1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Defensin, beta 1
NCBI Official Synonym Full Names
defensin, beta 1
NCBI Official Symbol
DEFB1
NCBI Official Synonym Symbols
BD1; HBD1; DEFB-1; DEFB101; MGC51822
UniProt Protein Name
Beta-defensin 1
UniProt Synonym Protein Names
Defensin, beta 1
Protein Family
UniProt Gene Name
DEFB1
UniProt Synonym Gene Names
BD1; HBD1
UniProt Entry Name
DEFB1_HUMAN
NCBI Protein Information
beta-defensin 1; BD-1; beta-defensin-1; OTTHUMP00000159500

NCBI Summary for DEFB1

Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis. [provided by RefSeq, Jul 2008]
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UniProt Comments for DEFB1

Function: Has bactericidal activity

Subcellular location: Secreted.

Tissue specificity: Plasma.

Sequence similarities: Belongs to the beta-defensin family.

Mass spectrometry: Molecular mass is 3928±0.5 Da from positions 33 - 68. Determined by ESI. Ref.5

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-DEFB1 antibody

 Reference Product  PubMed Publications
 CCR6 antibody  >3 publications with DEFB1 and CCR6
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