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CD152 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS312139

MBS312139 is an antibody targeting CD152 (CTLA-4). Also known as MAb to CD152 (CTLA-4). Reactive in Human. Host: Mouse. Hybridization of P3/X63 - Ag8.653 myeloma cells with spleen cells from BALB/c mice.Source: Ascites. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
CD152 (CTLA-4), Monoclonal Antibody
Full Product Name
MAb to CD152 (CTLA-4)
Product Synonym Names
Monoclonal Antibody to CD152 (CTLA-4)
Clonality
Monoclonal
Isotype
IgG2a
Host
Host: Mouse. Hybridization of P3/X63 - Ag8.653 myeloma cells with spleen cells from BALB/c mice.
Source: Ascites
Species Reactivity
Human
Form/Format
Purified; Lyophilized
Reconstitute with 1ml of distilled water.
Specificity
CD152 (CTLA-4)
Recognizes CD152 (CTAL-4). The "cytolytic T-lymphocyte-associated antigen 4" (CTLA-4) is a member of the Ig superfamily (1) and its extracellular domain exhibits a single Ig V-like region. It was originally identified as a fourth cDNA pr
Preparation and Storage
Store lyophilized product at 2 to 8 degree C. After reconstitution, aliquot and store at -20 degree C. Avoid multiple freeze/thaw cycles. The addition of 0.1% (w/v) sodium azide is recommended for storage of the reconstituted form for up to one month at 2
Immunogen
Human CTLA-4/human IgG heavy chain fusion protein (CTLA-4/Ig)
Affinity Constant
Not determined
Buffer
Lyophilized from PBS, pH 7.2 containing 1mg/ml BSA
Preservative
No
Lyophilized
Yes
Important Note
Centrifuge before opening to ensure complete recovery of vial contents.

Product Categories/Family for anti-CD152 (CTLA-4) antibody

Monoclonal Antibodies to Human CDs
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Application Notes for anti-CD152 (CTLA-4) antibody
Research studies by microscopy or flow cytometry, after in vitro activation of T cells with selected stimuli (Concanavalin A, or solid-phase fixed-CD3 + CD28 Mabs stimulation). Research studies on CTLA-4 expression on B cells and on CTLA-4 expression by i

Product References and Citations for anti-CD152 (CTLA-4) antibody

• Brunet, J.F., et al., (1987), "A new member of the immunoglobulin superfamily-CTLA-4", Nature, 328, 267-270.
• Linsley, P.S., et al., (1995), "Binding stoichiometry of the cytotoxic T lymphocyte-associated molecule-4 (CTLA-4", J.

Other Notes

Small volumes of anti-CD152 (CTLA-4) antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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