Epididymis Protein 4 (HE4) Human Protein

Name: HE4 Protein; Epididymis Protein 4; Human; MyBioSource
Brand: MyBioSource
SKU: MBS319909
Price: 605 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS319909

MBS319909 is a protein targeting HE4. Also known as Human Epididymis Protein 4. Host: Human Epididymis Cell Line Supernatant. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

Epididymis Protein 4 (HE4), Protein

Full Product Name

Human Epididymis Protein 4

Product Gene Name

HE4 protein

Host

Human Epididymis Cell Line Supernatant

Form/Format

Purified, Liquid

Preparation and Storage

Short-term store at 2-8 degree C and long term storage for one year at -20 degree C. Aliquot to avoid multiple freeze/thaw cycles.

Molecular Weight

19,333 Da

OMIM

601288

Buffer

Phosphate Buffered Saline, 50 mM EDTA, pH 7.4 + 0.1.

Perservative

None

Lyophilized

Warnings

The cell line supernatant was tested and found non-reactive for HIV1/HIV2 Ab, HBsAg, HCV Ab, HIV-1 and HCV by Nucleic Acid Test (NAT) per current FDA methods. Note that the samples tested were cell culture supernatant and the assays used were validated with serum samples. No test guarantees a product to be non-infectious. Therefore, all material derived from human fluids or tissues should be considered as potentially infectious.

Product Categories/Family for HE4 protein

Purified Reagents for Cancer Research

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Applications Tested/Suitable for HE4 protein

Chemiluminescent Immunoassay (CLIA)

Other Notes

Small volumes of HE4 protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for HE4. It may not necessarily be applicable to this product.

NCBI GI #

211947831

NCBI GeneID

7534

NCBI Accession #

ACJ13637.1

UniProt Secondary Accession #

P29213; P29312; Q32P43; Q5XJ08; Q6GPI2; Q6IN74; Q6NUR9; Q6P3U9; Q86V33; A8K1N0; B7Z465

UniProt Related Accession #

P63104

NCBI Official Full Name

epididymis luminal protein 4

NCBI Official Synonym Full Names

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta

NCBI Official Symbol

YWHAZ

NCBI Official Synonym Symbols

HEL4; YWHAD; KCIP-1; HEL-S-3; HEL-S-93; 14-3-3-zeta

UniProt Protein Name

14-3-3 protein zeta/delta

UniProt Synonym Protein Names

Protein kinase C inhibitor protein 1; KCIP-1

UniProt Gene Name

YWHAZ

UniProt Synonym Gene Names

KCIP-1

UniProt Entry Name

1433Z_HUMAN

NCBI Protein Information

14-3-3 protein zeta/delta

UniProt Comments for HE4

14-3-3 zeta: a protein of the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. A multifunctional regulator of the cell signaling processes. Phosphorylation apparently disrupts homodimerization.

Protein type: Adaptor/scaffold; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 8q23.1

Cellular Component: cell-cell adherens junction; cytoplasm; cytoplasmic vesicle membrane; cytosol; extracellular space; focal adhesion; nucleoplasm; nucleus

Molecular Function: identical protein binding; protein binding; protein kinase binding; transcription factor binding; ubiquitin protein ligase binding

Biological Process: establishment of Golgi localization; negative regulation of apoptosis; platelet activation; regulation of mRNA stability; signal transduction

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with HE4 protein

Reference Product	PubMed Publications
YWHAE protein	>6 publications with HE4 and YWHAE
CTNNB1 protein	>3 publications with HE4 and CTNNB1
BAD protein	>1 publications with HE4 and BAD
CDC25B protein	>1 publications with HE4 and CDC25B

Pathways associated with HE4 protein

Products by Pathway	Pathway Diagram
Activation Of BAD And Translocation To Mitochondria Pathway antibodies	Activation Of BAD And Translocation To Mitochondria Pathway Diagram
Activation Of BH3-only Proteins Pathway antibodies	Activation Of BH3-only Proteins Pathway Diagram
Adaptive Immune System Pathway antibodies	Adaptive Immune System Pathway Diagram
Alpha6-Beta4 Integrin Signaling Pathway antibodies	Alpha6-Beta4 Integrin Signaling Pathway Diagram
Apoptosis Pathway antibodies	Apoptosis Pathway Diagram
Calcium Regulation In The Cardiac Cell Pathway antibodies	Calcium Regulation In The Cardiac Cell Pathway Diagram
Cell Cycle Pathway antibodies	Cell Cycle Pathway Diagram
Cell Cycle Checkpoints Pathway antibodies	Cell Cycle Checkpoints Pathway Diagram
Cell Cycle Pathway antibodies	Cell Cycle Pathway Diagram
Cell Cycle Pathway antibodies	Cell Cycle Pathway Diagram

Diseases associated with HE4 protein

Disease Name	Pubmed Publications
Carcinoma Antibodies	>24 publications with HE4 and Carcinoma
Breast Neoplasms Antibodies	>13 publications with HE4 and Breast Neoplasms
Disease Models, Animal Antibodies	>13 publications with HE4 and Disease Models, Animal
Inflammation Antibodies	>10 publications with HE4 and Inflammation
Cardiovascular Diseases Antibodies	>10 publications with HE4 and Cardiovascular Diseases
Heart Diseases Antibodies	>8 publications with HE4 and Heart Diseases
Adenocarcinoma Antibodies	>8 publications with HE4 and Adenocarcinoma
Liver Diseases Antibodies	>8 publications with HE4 and Liver Diseases
Liver Neoplasms Antibodies	>7 publications with HE4 and Liver Neoplasms
Neoplasms, Experimental Antibodies	>7 publications with HE4 and Neoplasms, Experimental

Organs/Tissues associated with HE4 protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>38 publications with HE4 and Blood
Brain Antibodies	>29 publications with HE4 and Brain
Liver Antibodies	>25 publications with HE4 and Liver
Muscle Antibodies	>16 publications with HE4 and Muscle
Lung Antibodies	>14 publications with HE4 and Lung
Bone Antibodies	>13 publications with HE4 and Bone
Heart Antibodies	>13 publications with HE4 and Heart
Kidney Antibodies	>9 publications with HE4 and Kidney
Placenta Antibodies	>8 publications with HE4 and Placenta
Adipose Tissue Antibodies	>8 publications with HE4 and Adipose Tissue