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CCL11 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3200300

This is a rabbit polyclonal antibody against Ccl11. It was validated on Western BlotTarget Description: In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils (a prominent feature of allergic inflammatory… More details

$490 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Ccl11, Polyclonal Antibody
Full Product Name
Ccl11 antibody - C-terminal region
Product Gene Name
anti-CCL11 antibody
Product Synonym Gene Name
Scya11; eotaxin
Immunogen Sequence
Synthetic peptide located within the following region: LKSYKRITNN RCTLKAIVFK TRLGKEICAD PKKKWVQDAT KHLDQKLQTP
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
Ccl11 peptide (MBS3225190) is used for blocking the activity of Ccl11 antibody (MBS3200300)
Molecular Weight
11kDa
3D Structure
ModBase 3D Structure for P48298
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 87%; Horse: 100%; Human: 100%; Mouse: 90%; Pig: 92%; Rabbit: 91%; Rat: 90%

Product Categories/Family for anti-CCL11 antibody

Polyclonal; Disease Related
Applications Tested/Suitable for anti-CCL11 antibody
Western Blot (WB)

Western Blot (WB) of anti-CCL11 antibody

Host: Rabbit
Target Name: CCL11
Sample Tissue: Human Mouse Small Intestine
Antibody Dilution: 1ug/ml
Rabbit Anti-CCL11 Polyclonal Antibody – Cat# MBS3200300

Other Notes

Small volumes of anti-CCL11 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CCL11 purchase

MBS3200300 is an antibody targeting CCL11. Also known as Ccl11 antibody - C-terminal region. Reactive in Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CCL11. It may not necessarily be applicable to this product.

NCBI GI #
6755418
NCBI GeneID
20292
NCBI Accession #
NP_035460
UniProt Primary Accession #
P48298
UniProt Related Accession #
P48298
GenBank Nucleotide #
NM_011330
NCBI Official Full Name
eotaxin
NCBI Official Synonym Full Names
chemokine (C-C motif) ligand 11
NCBI Official Symbol
Ccl11
NCBI Official Synonym Symbols
Scya11; eotaxin
UniProt Protein Name
Eotaxin
UniProt Synonym Protein Names
C-C motif chemokine 11; Eosinophil chemotactic protein; Small-inducible cytokine A11
Protein Family
Eotaxin
UniProt Gene Name
Ccl11
UniProt Synonym Gene Names
Scya11
UniProt Entry Name
CCL11_MOUSE
NCBI Protein Information
eotaxin

UniProt Comments for CCL11

CCL11: In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions. Binds to CCR3. Belongs to the intercrine beta (chemokine CC) family.

Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide

Cellular Component: extracellular space; extracellular region; intracellular

Molecular Function: chemokine activity; cytokine activity

Biological Process: regulation of cell shape; positive regulation of angiogenesis; positive regulation of actin filament polymerization; mast cell chemotaxis; eosinophil chemotaxis; actin filament organization; immune response; cytoskeleton organization and biogenesis; positive regulation of endothelial cell proliferation; chemotaxis; inflammatory response; positive regulation of cell migration
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Research Articles on CCL11

1. Exogenous CCL11 was internalised in osteoclast and stimulated the migration of pre-osteoclast and concomitant increase in bone resorption.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-CCL11 antibody

 Products by Pathway  Pathway Diagram
 Asthma Pathway antibodies  Asthma Pathway Diagram
 Asthma Pathway antibodies  Asthma Pathway Diagram
 Chemokine Receptors Bind Chemokines Pathway antibodies  Chemokine Receptors Bind Chemokines Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies  Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram

Diseases associated with anti-CCL11 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >703 publications with CCL11 and Inflammation
 Respiratory Tract Diseases Antibodies  >573 publications with CCL11 and Respiratory Tract Diseases
 Hypersensitivity Antibodies  >565 publications with CCL11 and Hypersensitivity
 Asthma Antibodies  >511 publications with CCL11 and Asthma
 Lung Diseases Antibodies  >470 publications with CCL11 and Lung Diseases
 Respiratory Hypersensitivity Antibodies  >411 publications with CCL11 and Respiratory Hypersensitivity
 Necrosis Antibodies  >196 publications with CCL11 and Necrosis
 Bronchial Hyperreactivity Antibodies  >86 publications with CCL11 and Bronchial Hyperreactivity
 Drug Hypersensitivity Antibodies  >82 publications with CCL11 and Drug Hypersensitivity
 Dermatitis, Atopic Antibodies  >60 publications with CCL11 and Dermatitis, Atopic

Organs/Tissues associated with anti-CCL11 antibody

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >487 publications with CCL11 and Lung
 Intestine Antibodies  >56 publications with CCL11 and Intestine
 Eye Antibodies  >50 publications with CCL11 and Eye
 Thymus Antibodies  >28 publications with CCL11 and Thymus
 Embryonic Tissue Antibodies  >12 publications with CCL11 and Embryonic Tissue
 Mixed Antibodies  >10 publications with CCL11 and Mixed
 Mammary Gland Antibodies  >3 publications with CCL11 and Mammary Gland
 Tongue Antibodies  >2 publications with CCL11 and Tongue
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