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FOXE1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3200564

This is a rabbit polyclonal antibody against FOXE1. It was validated on Western Blot using a cell lysate as a positive control.Target Description: FOXE1 belongs to the forkhead family of transcription factors, which is characterized by a distinct forkhead… More details

$490 / 0.1 mL +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
FOXE1, Polyclonal Antibody
Full Product Name
FOXE1 antibody - middle region
Product Gene Name
Product Synonym Gene Name
FKHL15; FOXE2; HFKH4; HFKL5; TITF2; TTF-2; TTF2
Immunogen Sequence
Synthetic peptide located within the following region: APATTTGYQP AGCTGARPAN PSAYAAAYAG PDGAYPQGAG SAIFAAAGRL
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Cow, Guinea Pig, Human, Mouse, Pig, Rat
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
FOXE1 peptide (MBS3225615) is used for blocking the activity of FOXE1 antibody (MBS3200564)
Molecular Weight
38kDa
OMIM
241850
3D Structure
ModBase 3D Structure for O00358
Homology
Cow: 93%; Guinea Pig: 93%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human FOXE1
Applications Tested/Suitable for anti-FOXE1 antibody
Western Blot (WB)

Western Blot (WB) of anti-FOXE1 antibody

WB Suggested Anti-FOXE1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Human Muscle
Rabbit Anti-FOXE1 Polyclonal Antibody – Cat# MBS3200564

Other Notes

Small volumes of anti-FOXE1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FOXE1 purchase

MBS3200564 is an antibody targeting FOXE1. Also known as FOXE1 antibody - middle region. Reactive in Cow, Guinea Pig, Human, Mouse, Pig, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for FOXE1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
forkhead box protein E1
NCBI Official Synonym Full Names
forkhead box E1
NCBI Official Symbol
FOXE1
NCBI Official Synonym Symbols
TTF2; FOXE2; HFKH4; HFKL5; NMTC4; TITF2; TTF-2; FKHL15
UniProt Protein Name
Forkhead box protein E1
UniProt Synonym Protein Names
Forkhead box protein E2; Forkhead-related protein FKHL15; HFKH4; HNF-3/fork head-like protein 5; HFKL5; Thyroid transcription factor 2
Protein Family
UniProt Gene Name
FOXE1
UniProt Synonym Gene Names
FKHL15; FOXE2; TITF2; TTF2; HFKL5; TTF-2
UniProt Entry Name
FOXE1_HUMAN
NCBI Protein Information
forkhead box protein E1

NCBI Summary for FOXE1

This intronless gene encodes a protein that belongs to the forkhead family of transcription factors. Members of this family contain a conserved 100-amino acid DNA-binding 'forkhead' domain. The encoded protein functions as a thyroid transcription factor that plays a role in thyroid morphogenesis. Mutations in this gene are associated with the Bamforth-Lazarus syndrome, and with susceptibility to nonmedullary thyroid cancer-4. [provided by RefSeq, Nov 2016]
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UniProt Comments for FOXE1

FOXE1: Probable transcription factor. Could be involved in thyroid gland organogenesis. Defects in FOXE1 are the cause of Bamforth-Lazarus syndrome (BLS). BLS is associated with thyroid agenesis, cleft palate and choanal atresia.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 9q22

Cellular Component: nucleus

Molecular Function: DNA binding; sequence-specific DNA binding; transcription factor activity

Biological Process: transcription from RNA polymerase II promoter; anatomical structure morphogenesis; cell migration; hair follicle morphogenesis; thymus development; positive regulation of transcription, DNA-dependent; thyroid hormone generation; negative regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; embryonic organ morphogenesis; thyroid gland development; hard palate development; soft palate development; negative regulation of transcription, DNA-dependent

Disease: Hypothyroidism, Athyroidal, With Spiky Hair And Cleft Palate; Thyroid Cancer, Nonmedullary, 4
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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