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SP7 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3200809

This is a rabbit polyclonal antibody against SP7. It was validated on Western Blot using a cell lysate as a positive control.Target Description: SP7 is a C2H2-type zinc finger transcription factor of the SP gene family and a putative master regulator of bone… More details

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Product Overview

Online Datasheet in PDF
Product Name
SP7, Polyclonal Antibody
Full Product Name
SP7 antibody - N-terminal region
Product Gene Name
Product Synonym Gene Name
MGC126598; OSX; osterix; OI11; OI12
Immunogen Sequence
Synthetic peptide located within the following region: MASSLLEEEV HYGSSPLAML TAACSKFGGS SPLRDSTTLG KAGTKKPYSV
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
SP7 peptide (MBS3225851) is used for blocking the activity of SP7 antibody (MBS3200809)
Molecular Weight
45kDa
OMIM
AF466179 mRNA
3D Structure
ModBase 3D Structure for Q8TDD2
Homology
Cow: 100%; Dog: 93%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 93%; Rat: 86%
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human SP7
Applications Tested/Suitable for anti-SP7 antibody
Immunohistochemistry (IHC), Western Blot (WB)

Immunohistochemistry (IHC) of anti-SP7 antibody

Immunohistochemistry with Testis tissue at an antibody concentration of 5ug/ml using anti-SP7 antibody
Rabbit Anti-SP7 Polyclonal Antibody – Cat# MBS3200809

Western Blot (WB) of anti-SP7 antibody

Host: Rabbit
Target Name: SP7
Sample Tissue: Human Fetal Lung
Antibody Dilution: 1.0ug/ml
Rabbit Anti-SP7 Polyclonal Antibody, Western Blot (WB) – Cat# MBS3200809

Western Blot (WB) of anti-SP7 antibody

WB Suggested Anti-SP7 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Human kidney
Rabbit Anti-SP7 Polyclonal Antibody, Western Blot (WB) – Cat# MBS3200809

Other Notes

Small volumes of anti-SP7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SP7 purchase

MBS3200809 is an antibody targeting SP7. Also known as SP7 antibody - N-terminal region. Reactive in Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SP7. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
transcription factor Sp7 isoform a
NCBI Official Synonym Full Names
Sp7 transcription factor
NCBI Official Symbol
SP7
NCBI Official Synonym Symbols
OSX; OI11; OI12; osterix
UniProt Protein Name
Transcription factor Sp7
UniProt Synonym Protein Names
Zinc finger protein osterix
Protein Family
UniProt Gene Name
SP7
UniProt Synonym Gene Names
OSX
NCBI Protein Information
transcription factor Sp7

NCBI Summary for SP7

This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein is a bone specific transcription factor and is required for osteoblast differentiation and bone formation.[provided by RefSeq, Jul 2010]
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UniProt Comments for SP7

Transcriptional activator essential for osteoblast differentiation. Binds to SP1 and EKLF consensus sequences and to other G/C-rich sequences ().

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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