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TRAFD1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3201187

This is a rabbit polyclonal antibody against TRAFD1. It was validated on Western Blot and immunohistochemistryTarget Description: TRAFD1 is a new candidate transcription factor. More details

$490 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TRAFD1, Polyclonal Antibody
Full Product Name
TRAFD1 antibody - C-terminal region
Product Gene Name
Product Synonym Gene Name
FLN29
Immunogen Sequence
Synthetic peptide located within the following region: TATNHVTEGI PRLDSQPQET SPELPRRRVR HQGDLSSGYL DDTKQETANG
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
TRAFD1 peptide (MBS3226212) is used for blocking the activity of TRAFD1 antibody (MBS3201187)
Molecular Weight
65kDa
OMIM
AB007447 mRNA
3D Structure
ModBase 3D Structure for O14545
Homology
Cow: 79%; Dog: 86%; Guinea Pig: 93%; Horse: 86%; Human: 100%; Mouse: 85%; Rabbit: 86%; Rat: 86%
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human TRAFD1
Applications Tested/Suitable for anti-TRAFD1 antibody
Immunohistochemistry (IHC), Western Blot (WB)

Immunohistochemistry (IHC) of anti-TRAFD1 antibody

Human kidney
Rabbit Anti-TRAFD1 Polyclonal Antibody – Cat# MBS3201187

Western Blot (WB) of anti-TRAFD1 antibody

WB Suggested Anti-TRAFD1 Antibody Titration: 0.2-1 ug/ml
Positive Control: Raji cell lysateTRAFD1 is strongly supported by BioGPS gene expression data to be expressed in Human Raji cells
Rabbit Anti-TRAFD1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS3201187

Other Notes

Small volumes of anti-TRAFD1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TRAFD1 purchase

MBS3201187 is an antibody targeting TRAFD1. Also known as TRAFD1 antibody - C-terminal region. Reactive in Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TRAFD1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
TRAF-type zinc finger domain-containing protein 1
NCBI Official Synonym Full Names
TRAF-type zinc finger domain containing 1
NCBI Official Symbol
TRAFD1
NCBI Official Synonym Symbols
FLN29
UniProt Protein Name
TRAF-type zinc finger domain-containing protein 1
UniProt Synonym Protein Names
Protein FLN29
UniProt Gene Name
TRAFD1
UniProt Synonym Gene Names
FLN29
NCBI Protein Information
TRAF-type zinc finger domain-containing protein 1

NCBI Summary for TRAFD1

The innate immune system confers host defense against viral and microbial infection, and TRAFD1 is a negative feedback regulator that controls excessive immune responses (Sanada et al., 2008 [PubMed 18849341]).[supplied by OMIM, Dec 2009]

UniProt Comments for TRAFD1

Negative feedback regulator that controls excessive innate immune responses. Regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. May inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation. May negatively regulate the RLH pathway downstream from MAVS and upstream of NF-kappa-B and IRF3 ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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