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WDHD1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3201201

This is a rabbit polyclonal antibody against WDHD1. It was validated on Western Blot using a cell lysate as a positive control.Target Description: WDHD1 contains multiple N-terminal WD40 domains and a C-terminal high mobility group (HMG) box. WD40 domains are… More details

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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
WDHD1, Polyclonal Antibody
Full Product Name
WDHD1 antibody - middle region
Product Gene Name
Product Synonym Gene Name
AND-1; CTF4; CHTF4
Immunogen Sequence
Synthetic peptide located within the following region: KQILHGDPLP LTRKSYLAWI GFSAEGTPCY VDSEGIVRML NRGLGNTWTP
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Specificity
Reactive with the SepB fragment (428-850aa) of WDHD1.
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
WDHD1 peptide (MBS3226225) is used for blocking the activity of WDHD1 antibody (MBS3201201)
Molecular Weight
126kDa
OMIM
608126
3D Structure
ModBase 3D Structure for O75717
Homology
Cow: 100%; Dog: 100%; Horse: 93%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 100%; Rat: 93%
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human WDHD1
Applications Tested/Suitable for anti-WDHD1 antibody
Western Blot (WB)

Western Blot (WB) of anti-WDHD1 antibody

WB Suggested Anti-WDHD1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:12500
Positive Control: HepG2 cell lysate
Rabbit Anti-WDHD1 Polyclonal Antibody – Cat# MBS3201201

Other Notes

Small volumes of anti-WDHD1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for WDHD1 purchase

MBS3201201 is an antibody targeting WDHD1. Also known as WDHD1 antibody - middle region. Reactive in Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for WDHD1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
WD repeat and HMG-box DNA-binding protein 1 isoform 1
NCBI Official Synonym Full Names
WD repeat and HMG-box DNA binding protein 1
NCBI Official Symbol
WDHD1
NCBI Official Synonym Symbols
AND1; CTF4; AND-1; CHTF4
UniProt Protein Name
WD repeat and HMG-box DNA-binding protein 1
UniProt Synonym Protein Names
Acidic nucleoplasmic DNA-binding protein 1; And-1
UniProt Gene Name
WDHD1
UniProt Synonym Gene Names
AND1; And-1
UniProt Entry Name
WDHD1_HUMAN
NCBI Protein Information
WD repeat and HMG-box DNA-binding protein 1

NCBI Summary for WDHD1

The protein encoded by this gene contains multiple N-terminal WD40 domains and a C-terminal high mobility group (HMG) box. WD40 domains are found in a variety of eukaryotic proteins and may function as adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. HMG boxes are found in many eukaryotic proteins involved in chromatin assembly, transcription and replication. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
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UniProt Comments for WDHD1

WDHD1: Acts as a replication initiation factor that brings together the MCM2-7 helicase and the DNA polymerase alpha/primase complex in order to initiate DNA replication.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 14q22.2

Cellular Component: nucleoplasm; cytoplasm; chromosome, pericentric region

Molecular Function: protein binding; DNA binding; RNA binding; chromatin binding

Biological Process: RNA processing; regulation of chromosome organization and biogenesis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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