• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

KLF8 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3201209

This is a rabbit polyclonal antibody against KLF8. It was validated on Western Blot using a cell lysate as a positive control.Target Description: KLF8 is abnormally expressed in female patients with X autosome translocation t(X;21)(p11.2;q22.3) and… More details

$490 / 0.1 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
KLF8, Polyclonal Antibody
Full Product Name
KLF8 antibody - middle region
Product Gene Name
Product Synonym Gene Name
BKLF3; DKFZp686O08126; DXS741; MGC138314; ZNF741
Immunogen Sequence
Synthetic peptide located within the following region: LEIPSDSEES TIESGSSALQ SLQGLQQEPA AMAQMQGGES LDLKRRRIHQ
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
KLF8 peptide (MBS3226233) is used for blocking the activity of KLF8 antibody (MBS3201209)
Molecular Weight
39kDa
OMIM
300286
3D Structure
ModBase 3D Structure for O95600
Homology
Dog: 100%; Guinea Pig: 86%; Horse: 83%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93%
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human KLF8
Applications Tested/Suitable for anti-KLF8 antibody
Western Blot (WB)

Western Blot (WB) of anti-KLF8 antibody

Host: Mouse
Target Name: KLF8
Sample Tissue: Mouse Kidney
Antibody Dilution: 1ug/ml
Rabbit Anti-KLF8 Polyclonal Antibody – Cat# MBS3201209

Western Blot (WB) of anti-KLF8 antibody

Host: Rabbit
Target Name: KLF8
Sample Type: HepG2 Whole Cell lysates
Antibody Dilution: 1.0ug/ml
Rabbit Anti-KLF8 Polyclonal Antibody, Western Blot (WB) – Cat# MBS3201209

Western Blot (WB) of anti-KLF8 antibody

WB Suggested Anti-KLF8 Antibody Titration: 0.2-1 ug/ml
Positive Control: HepG2 cell lysate
Rabbit Anti-KLF8 Polyclonal Antibody, Western Blot (WB) – Cat# MBS3201209

Other Notes

Small volumes of anti-KLF8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KLF8 purchase

MBS3201209 is an antibody targeting KLF8. Also known as KLF8 antibody - middle region. Reactive in Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for KLF8. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
Krueppel-like factor 8 isoform 1
NCBI Official Synonym Full Names
Kruppel like factor 8
NCBI Official Symbol
KLF8
NCBI Official Synonym Symbols
BKLF3; ZNF741
UniProt Protein Name
Krueppel-like factor 8
UniProt Synonym Protein Names
Basic krueppel-like factor 3; Zinc finger protein 741
Protein Family
UniProt Gene Name
KLF8
UniProt Synonym Gene Names
BKLF3; ZNF741
UniProt Entry Name
KLF8_HUMAN
NCBI Protein Information
Krueppel-like factor 8

NCBI Summary for KLF8

This gene encodes a protein which is a member of the Sp/KLF family of transcription factors. Members of this family contain a C-terminal DNA-binding domain with three Kruppel-like zinc fingers. The encoded protein is thought to play an important role in the regulation of epithelial to mesenchymal transition, a process which occurs normally during development but also during metastasis. A pseudogene has been identified on chromosome 16. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]
Show more

UniProt Comments for KLF8

KLF8: Transcriptional repressor and activator. Binds to CACCC- boxes promoter elements. Also binds the GT-box of cyclin D1 promoter and mediates cell cycle progression at G(1) phase as a downstream target of focal adhesion kinase (FAK). Belongs to the Sp1 C2H2-type zinc-finger protein family.

Protein type: C2H2-type zinc finger protein; Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: Xp11.21

Cellular Component: nucleus

Molecular Function: DNA binding; metal ion binding

Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-KLF8 antibody

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000