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ARID3A Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3201213

This is a rabbit polyclonal antibody against ARID3A. It was validated on Western Blot using a cell lysate as a positive control.Target Description: ARID3A is a member of the ARID (AT-rich interaction domain) family of proteins which bind DNA. Other ARID… More details

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Product Overview

Online Datasheet in PDF
Product Name
ARID3A, Polyclonal Antibody
Full Product Name
ARID3A antibody - middle region
Product Gene Name
anti-ARID3A antibody
Product Synonym Gene Name
DRIL1; DRIL3; BRIGHT; E2FBP1
Immunogen Sequence
Synthetic peptide located within the following region: QAAIDSNRRE GRRQSFGGSL FAYSPGGAHG MLSSPKLPVS SLGLAASTNG
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rat, Zebrafish
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
ARID3A peptide (MBS3226237) is used for blocking the activity of ARID3A antibody (MBS3201213)
Molecular Weight
63kDa
OMIM
603265
3D Structure
ModBase 3D Structure for Q99856
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 92%; Horse: 92%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%; Zebrafish: 77%
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human ARID3A

Product Categories/Family for anti-ARID3A antibody

Polyclonal; Transcription Factor; Transcription Regulation; Transcription Regulation; Chromatin & Nuclear Signaling; Developmental Biology; Stem Cells; Epigenetics; Meiosis/Mitosis/Cell Cycle; Transcription Factors
Applications Tested/Suitable for anti-ARID3A antibody
Western Blot (WB)

Western Blot (WB) of anti-ARID3A antibody

WB Suggested Anti-ARID3A Antibody Titration: 0.2-1 ug/ml
Positive Control: HepG2 cell lysateARID3A is supported by BioGPS gene expression data to be expressed in HepG2
Rabbit Anti-ARID3A Polyclonal Antibody – Cat# MBS3201213

Other Notes

Small volumes of anti-ARID3A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ARID3A purchase

MBS3201213 is an antibody targeting ARID3A. Also known as ARID3A antibody - middle region. Reactive in Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rat, Zebrafish. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ARID3A. It may not necessarily be applicable to this product.

NCBI GI #
4885193
NCBI GeneID
1820
NCBI Accession #
NP_005215
UniProt Primary Accession #
Q99856
UniProt Related Accession #
Q99856
GenBank Nucleotide #
NM_005224
NCBI Official Full Name
AT-rich interactive domain-containing protein 3A
NCBI Official Synonym Full Names
AT-rich interaction domain 3A
NCBI Official Symbol
ARID3A
NCBI Official Synonym Symbols
DRIL1; DRIL3; BRIGHT; E2FBP1
UniProt Protein Name
AT-rich interactive domain-containing protein 3A
UniProt Synonym Protein Names
B-cell regulator of IgH transcription; Bright; Dead ringer-like protein 1; E2F-binding protein 1
Protein Family
AT-rich interactive domain-containing protein
UniProt Gene Name
ARID3A
UniProt Synonym Gene Names
DRIL1; DRIL3; DRX; E2FBP1; ARID domain-containing protein 3A; Bright
UniProt Entry Name
ARI3A_HUMAN
NCBI Protein Information
AT-rich interactive domain-containing protein 3A

NCBI Summary for ARID3A

This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA binding proteins. It was found by homology to the Drosophila dead ringer gene, which is important for normal embryogenesis. Other ARID family members have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation, and possibly in chromatin structure modification. [provided by RefSeq, Jul 2008]
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UniProt Comments for ARID3A

Bright: a member of the ARID (AT-rich interaction domain) family of transcription factors. It was found by its homology to the Drosophila dead ringer protein, which is important for normal embryogenesis. Binds a VH promoter proximal site necessary for induced mu-heavy-chain transcription. Binds the minor groove of a restricted ATC sequence that is sufficient for nuclear matrix association. This sequence motif is present in matrix-associating regions (MARS) proximal to the promoter and flanking E mu. Activates E mu-driven transcription by binding these sites. Contributes to localized control of accessibility and therefore nonrandom gene use during V(D)J recombination.

Protein type: Transcription factor

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: nucleoplasm; Golgi apparatus; cytoplasm; nucleolus; lipid raft

Molecular Function: protein binding; protein homodimerization activity; chromatin binding

Biological Process: transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter
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Research Articles on ARID3A

1. Data indicate ARID3a(+) B cells as a type of effector B cell, and link ARID3a expression in B lymphocytes to interferon alpha (IFNa)-associated inflammatory responses in systemic lupus erythematosus (SLE).

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ARID3A antibody

 Reference Product  PubMed Publications
 BTK antibody  >6 publications with ARID3A and BTK
 PML antibody  >4 publications with ARID3A and PML
 SP100 antibody  >1 publications with ARID3A and SP100
 SUMO1 antibody  >1 publications with ARID3A and SUMO1
 SP140 antibody  >1 publications with ARID3A and SP140
 TP53 antibody  >1 publications with ARID3A and TP53

Pathways associated with anti-ARID3A antibody

 Products by Pathway  Pathway Diagram
 Direct P53 Effectors Pathway antibodies  Direct P53 Effectors Pathway Diagram

Diseases associated with anti-ARID3A antibody

 Disease Name  Pubmed Publications
 Translocation, Genetic Antibodies  >1 publications with ARID3A and Translocation, Genetic
 Brain Diseases Antibodies  >1 publications with ARID3A and Brain Diseases
 Kidney Diseases Antibodies  >1 publications with ARID3A and Kidney Diseases

Organs/Tissues associated with anti-ARID3A antibody

 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >3 publications with ARID3A and Bone
 Lymph Node Antibodies  >2 publications with ARID3A and Lymph Node
 Embryonic Tissue Antibodies  >2 publications with ARID3A and Embryonic Tissue
 Ovary Antibodies  >1 publications with ARID3A and Ovary
 Liver Antibodies  >1 publications with ARID3A and Liver
 Kidney Antibodies  >1 publications with ARID3A and Kidney
 Placenta Antibodies  >1 publications with ARID3A and Placenta
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