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ZMYND8 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3202353

This is a rabbit polyclonal antibody against ZMYND8. It was validated on Western BlotTarget Description: The protein encoded by this gene is a receptor for activated C-kinase (RACK) protein. The encoded protein has been shown to bind in vitro to activated… More details

$490 / 0.1 mL +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
ZMYND8, Polyclonal Antibody
Full Product Name
ZMYND8 Antibody - C-terminal region
Product Gene Name
anti-ZMYND8 antibody
Immunogen Sequence
Synthetic peptide located within the following region: LDLSGSRETP SSILLGSNQG SDHSRSNKSS WSSSDEKRGS TRSDHNTSTS
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Cow, Dog, Horse, Human, Mouse, Rat
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
ZMYND8 peptide (MBS3227331) is used for blocking the activity of ZMYND8 antibody (MBS3202353)
Molecular Weight
84kDa
3D Structure
ModBase 3D Structure for Q9ULU4
Homology
Cow: 85%; Dog: 92%; Horse: 92%; Human: 100%; Mouse: 77%; Rat: 86%
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human ZMYND8

Product Categories/Family for anti-ZMYND8 antibody

Polyclonal; Transcription Factor; Cell Biology; Signal Transduction; Disease Related
Applications Tested/Suitable for anti-ZMYND8 antibody
Western Blot (WB)

Western Blot (WB) of anti-ZMYND8 antibody

Host: Rabbit
Target Name: ZMYND8
Sample Type: Thymus Tumor lysates
Antibody Dilution: 1.0ug/ml
Rabbit Anti-ZMYND8 Polyclonal Antibody – Cat# MBS3202353

Other Notes

Small volumes of anti-ZMYND8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ZMYND8 purchase

MBS3202353 is an antibody targeting ZMYND8. Also known as ZMYND8 Antibody - C-terminal region. Reactive in Cow, Dog, Horse, Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ZMYND8. It may not necessarily be applicable to this product.

NCBI GI #
34335266
NCBI GeneID
23613
NCBI Accession #
NP_036540.3
UniProt Primary Accession #
Q9ULU4
UniProt Related Accession #
Q9ULU4
GenBank Nucleotide #
NM_012408.5
NCBI Official Full Name
protein kinase C-binding protein 1 isoform b
NCBI Official Synonym Full Names
zinc finger MYND-type containing 8
NCBI Official Symbol
ZMYND8
NCBI Official Synonym Symbols
RACK7; PRKCBP1; PRO2893
UniProt Protein Name
Protein kinase C-binding protein 1
UniProt Synonym Protein Names
Cutaneous T-cell lymphoma-associated antigen se14-3; CTCL-associated antigen se14-3; Rack7; Zinc finger MYND domain-containing protein 8
Protein Family
Protein kinase C-binding protein
UniProt Gene Name
ZMYND8
UniProt Synonym Gene Names
KIAA1125; PRKCBP1; RACK7; CTCL-associated antigen se14-3
UniProt Entry Name
PKCB1_HUMAN
NCBI Protein Information
protein kinase C-binding protein 1

NCBI Summary for ZMYND8

The protein encoded by this gene is a receptor for activated C-kinase (RACK) protein. The encoded protein has been shown to bind in vitro to activated protein kinase C beta I. In addition, this protein is a cutaneous T-cell lymphoma-associated antigen. Finally, the protein contains a bromodomain and two zinc fingers, and is thought to be a transcriptional regulator. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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UniProt Comments for ZMYND8

RACK7: a DNA damage response (DDR) protein, receptor for activated C-kinase (RACK) protein, and a transcriptional regulator. A bromodomain (BRD)-containing protein that recruits the nucleosome remodeling and histone deacetylation (NuRD) complex to damaged chromatin. Targets DNA damage within actively transcribed regions, repressing transcription, and promoting repair by homologous recombination. A cutaneous T-cell lymphoma-associated antigen that contains a bromodomain and two zinc fingers. Twenty-two alternatively spliced isoforms of the human protein hve been reported. Note: This description may include information from UniProtKB

Protein type: Transcription regulation

Chromosomal Location of Human Ortholog: 20q13.12

Cellular Component: nucleus

Molecular Function: protein binding; zinc ion binding

Biological Process: negative regulation of transcription from RNA polymerase II promoter
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Research Articles on ZMYND8

1. Drebrin may regulate activities of epigenetic reader ZMYND8 via its cytoplasmic sequestration.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-ZMYND8 antibody

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