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KCNJ9 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3202460

This is a rabbit polyclonal antibody against KCNJ9. It was validated on Western Blot using a cell lysate as a positive control.Target Description: Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic… More details

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Product Overview

Online Datasheet in PDF
Product Name
KCNJ9, Polyclonal Antibody
Full Product Name
KCNJ9 antibody - middle region
Product Gene Name
anti-KCNJ9 antibody
Product Synonym Gene Name
GIRK3; KIR3.3
Immunogen Sequence
Synthetic peptide located within the following region: CQARSSYLVD EVLWGHRFTS VLTLEDGFYE VDYASFHETF EVPTPSCSAR
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
KCNJ9 peptide (MBS3227438) is used for blocking the activity of KCNJ9 antibody (MBS3202460)
Molecular Weight
44kDa
OMIM
600932
3D Structure
ModBase 3D Structure for Q92806
Homology
Cow: 100%; Dog: 93%; Goat: 93%; Guinea Pig: 100%; Horse: 77%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 92%
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human KCNJ9

Product Categories/Family for anti-KCNJ9 antibody

Polyclonal; Ion Channel; Membrane Protein
Applications Tested/Suitable for anti-KCNJ9 antibody
Western Blot (WB)

Western Blot (WB) of anti-KCNJ9 antibody

WB Suggested Anti-KCNJ9 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: NCI-H226 cell lysateKCNJ9 is supported by BioGPS gene expression data to be expressed in NCIH226
Rabbit Anti-KCNJ9 Polyclonal Antibody – Cat# MBS3202460

Other Notes

Small volumes of anti-KCNJ9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KCNJ9 purchase

MBS3202460 is an antibody targeting KCNJ9. Also known as KCNJ9 antibody - middle region. Reactive in Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for KCNJ9. It may not necessarily be applicable to this product.

NCBI GI #
25121970
NCBI GeneID
3765
NCBI Accession #
NP_004974
UniProt Primary Accession #
Q92806
UniProt Related Accession #
Q92806
GenBank Nucleotide #
NM_004983
NCBI Official Full Name
G protein-activated inward rectifier potassium channel 3
NCBI Official Synonym Full Names
potassium voltage-gated channel subfamily J member 9
NCBI Official Symbol
KCNJ9
NCBI Official Synonym Symbols
GIRK3; KIR3.3
UniProt Protein Name
G protein-activated inward rectifier potassium channel 3
UniProt Synonym Protein Names
Inward rectifier K(+) channel Kir3.3; Potassium channel, inwardly rectifying subfamily J member 9
Protein Family
G protein-activated inward rectifier potassium channel
UniProt Gene Name
KCNJ9
UniProt Synonym Gene Names
GIRK3; GIRK-3
UniProt Entry Name
IRK9_HUMAN
NCBI Protein Information
G protein-activated inward rectifier potassium channel 3

NCBI Summary for KCNJ9

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins. It associates with another G-protein-activated potassium channel to form a heteromultimeric pore-forming complex. [provided by RefSeq, Jul 2008]
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UniProt Comments for KCNJ9

GIRK3: This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ9 subfamily.

Protein type: Membrane protein, multi-pass; Channel, potassium; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q23.2

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: protein binding; G-protein activated inward rectifier potassium channel activity; PDZ domain binding

Biological Process: synaptic transmission; potassium ion import
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Research Articles on KCNJ9

1. This study is the first to identify the expression of GIRK2-4 subunits in human esophageal smooth muscle cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-KCNJ9 antibody

 Reference Product  PubMed Publications
 KCNJ3 antibody  >5 publications with KCNJ9 and KCNJ3

Pathways associated with anti-KCNJ9 antibody

 Products by Pathway  Pathway Diagram
 Activation Of G Protein Gated Potassium Channels Pathway antibodies  Activation Of G Protein Gated Potassium Channels Pathway Diagram
 Activation Of GABAB Receptors Pathway antibodies  Activation Of GABAB Receptors Pathway Diagram
 Circadian Entrainment Pathway antibodies  Circadian Entrainment Pathway Diagram
 Circadian Entrainment Pathway antibodies  Circadian Entrainment Pathway Diagram
 Dopaminergic Synapse Pathway antibodies  Dopaminergic Synapse Pathway Diagram
 Dopaminergic Synapse Pathway antibodies  Dopaminergic Synapse Pathway Diagram
 Estrogen Signaling Pathway antibodies  Estrogen Signaling Pathway Diagram
 Estrogen Signaling Pathway antibodies  Estrogen Signaling Pathway Diagram
 G Protein Gated Potassium Channels Pathway antibodies  G Protein Gated Potassium Channels Pathway Diagram
 GABA B Receptor Activation Pathway antibodies  GABA B Receptor Activation Pathway Diagram

Diseases associated with anti-KCNJ9 antibody

 Disease Name  Pubmed Publications
 Seizures Antibodies  >1 publications with KCNJ9 and Seizures

Organs/Tissues associated with anti-KCNJ9 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >21 publications with KCNJ9 and Brain
 Connective Tissue Antibodies  >1 publications with KCNJ9 and Connective Tissue
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