Rabbit Anti-P2RX6 Polyclonal Antibody – Cat# MBS3202461

WB Suggested Anti-P2RXL1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: ACHN cell lysate

P2RXL1 (P2RX6) Antibody – Rabbit Polyclonal

Name: P2RX6 Antibody; Polyclonal; Rabbit; MyBioSource
Brand: MyBioSource
SKU: MBS3202461
Price: 490 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3202461

This is a rabbit polyclonal antibody against P2RXL1. It was validated on Western Blot using a cell lysate as a positive control.Target Description: The protein encoded by this gene belongs to the family of P2X receptors, which are ATP-gated ion channels and… More details

$490 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

P2RXL1 (P2RX6), Polyclonal Antibody

Full Product Name

P2RXL1 antibody - N-terminal region

Product Gene Name

anti-P2RX6 antibody

Product Synonym Gene Name

MGC129625; P2RX6; P2X6; P2XM; P2RXL1

Immunogen Sequence

Synthetic peptide located within the following region: NWRVGALQRL LQFGIVVYVV GWALLAKKGY QERDLEPQFS IITKLKGVSV

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat

Form/Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Purity/Purification

Affinity Purified

Preparation and Storage

For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Antibody/Peptide Pairs

P2RXL1 peptide (MBS3227439) is used for blocking the activity of P2RXL1 antibody (MBS3202461)

Molecular Weight

49kDa

OMIM

608077

3D Structure

ModBase 3D Structure for O15547

Homology

Cow: 77%; Dog: 79%; Guinea Pig: 77%; Horse: 77%; Human: 100%; Mouse: 79%; Rabbit: 79%; Rat: 77%

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human P2RXL1

Product Categories/Family for anti-P2RX6 antibody

Polyclonal; Ion Channel; Cell Biology

Applications Tested/Suitable for anti-P2RX6 antibody

Western Blot (WB)

Other Notes

Small volumes of anti-P2RX6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for P2RX6 purchase

MBS3202461 is an antibody targeting P2RX6. Also known as P2RXL1 antibody - N-terminal region. Reactive in Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for P2RX6. It may not necessarily be applicable to this product.

NCBI GI #

157419148

NCBI GeneID

9127

NCBI Accession #

NP_005437

UniProt Primary Accession #

O15547

UniProt Related Accession #

O15547

GenBank Nucleotide #

NM_005446

NCBI Official Full Name

P2X purinoceptor 6 isoform 1

NCBI Official Synonym Full Names

purinergic receptor P2X 6

NCBI Official Symbol

P2RX6

NCBI Official Synonym Symbols

P2X6; P2XM; P2RXL1

UniProt Protein Name

P2X purinoceptor 6

UniProt Synonym Protein Names

ATP receptor; P2XM; Purinergic receptor; Purinergic receptor P2X-like 1

Protein Family

P2X purinoceptor

UniProt Gene Name

P2RX6

UniProt Synonym Gene Names

P2RXL1; P2X6; P2X6

UniProt Entry Name

P2RX6_HUMAN

NCBI Protein Information

P2X purinoceptor 6

NCBI Summary for P2RX6

The protein encoded by this gene belongs to the family of P2X receptors, which are ATP-gated ion channels and mediate rapid and selective permeability to cations. This gene is predominantly expressed in skeletal muscle, and regulated by p53. The encoded protein is associated with VE-cadherin at the adherens junctions of human umbilical vein endothelial cells. Alternative splicing results in multiple transcript variants. A related pseudogene, which is also located on chromosome 22, has been identified. [provided by RefSeq, Apr 2009]

UniProt Comments for P2RX6

P2X6: Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; Channel, cation; Receptor, misc.; Channel, ligand-gated

Chromosomal Location of Human Ortholog: 22q11.21

Cellular Component: cell soma; integral to plasma membrane; postsynaptic density; cytoplasm; dendritic spine; integral to nuclear inner membrane; cell junction

Molecular Function: identical protein binding; transmembrane receptor activity; channel activity; purinergic nucleotide receptor activity; ATP binding; ATP-gated cation channel activity

Biological Process: muscle contraction; transport; protein heterooligomerization; signal transduction; transmembrane transport; protein homooligomerization; cation transport

Research Articles on P2RX6

1. one subunit of P2X2 and two subunits of P2X3 form P2X2/3 heteromeric receptors, whereas two subunits of P2X2 and one subunit of P2X6 constitute P2X2/6 receptors

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.