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VDAC3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3202465

This is a rabbit polyclonal antibody against VDAC3. It was validated on Western Blot using a cell lysate as a positive control.Target Description: VDAC3 belongs to a group of mitochondrial membrane channels involved in translocation of adenine nucleotides… More details

$490 / 0.1 mL +1 FREE 8GB USB
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
VDAC3, Polyclonal Antibody
Full Product Name
VDAC3 antibody - N-terminal region
Product Gene Name
Product Synonym Gene Name
HD-VDAC3; VDAC-3
Immunogen Sequence
Synthetic peptide located within the following region: SCSGVEFSTS GHAYTDTGKA SGNLETKYKV CNYGLTFTQK WNTDNTLGTE
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
VDAC3 peptide (MBS3227443) is used for blocking the activity of VDAC3 antibody (MBS3202465)
Molecular Weight
31kDa
OMIM
610029
3D Structure
ModBase 3D Structure for Q9Y277
Homology
Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 92%
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human VDAC3
Applications Tested/Suitable for anti-VDAC3 antibody
Western Blot (WB)

Western Blot (WB) of anti-VDAC3 antibody

Host: Rabbit
Target Name: VDAC3
Sample Type: HT1080
Antibody Dilution: 1.0ug/ml
Rabbit Anti-VDAC3 Polyclonal Antibody – Cat# MBS3202465

Western Blot (WB) of anti-VDAC3 antibody

Host: Rabbit
Target Name: VDAC3
Sample Type: RPMI-8226
Antibody Dilution: 1.0ug/ml
Rabbit Anti-VDAC3 Polyclonal Antibody, Western Blot (WB) – Cat# MBS3202465

Western Blot (WB) of anti-VDAC3 antibody

WB Suggested Anti-VDAC3 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:12500
Positive Control: Human Thymus
Rabbit Anti-VDAC3 Polyclonal Antibody, Western Blot (WB) – Cat# MBS3202465

Other Notes

Small volumes of anti-VDAC3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for VDAC3 purchase

MBS3202465 is an antibody targeting VDAC3. Also known as VDAC3 antibody - N-terminal region. Reactive in Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for VDAC3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
voltage-dependent anion-selective channel protein 3 isoform 1
NCBI Official Synonym Full Names
voltage dependent anion channel 3
NCBI Official Symbol
VDAC3
NCBI Official Synonym Symbols
VDAC-3; HD-VDAC3
UniProt Protein Name
Voltage-dependent anion-selective channel protein 3
UniProt Synonym Protein Names
Outer mitochondrial membrane protein porin 3
UniProt Gene Name
VDAC3
UniProt Synonym Gene Names
VDAC-3; hVDAC3
UniProt Entry Name
VDAC3_HUMAN
NCBI Protein Information
voltage-dependent anion-selective channel protein 3

NCBI Summary for VDAC3

This gene encodes a voltage-dependent anion channel (VDAC), and belongs to the mitochondrial porin family. VDACs are small, integral membrane proteins that traverse the outer mitochondrial membrane and conduct ATP and other small metabolites. They are known to bind several kinases of intermediary metabolism, thought to be involved in translocation of adenine nucleotides, and are hypothesized to form part of the mitochondrial permeability transition pore, which results in the release of cytochrome c at the onset of apoptotic cell death. Alternatively transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
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UniProt Comments for VDAC3

VDAC3: a protein of the eukaryotic mitochondrial porin family. Forms a voltage-dependent anion channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. Two splice-variant isoforms have been described.

Protein type: Channel, misc.; Mitochondrial; Membrane protein, integral

Chromosomal Location of Human Ortholog: 8p11.2

Cellular Component: pore complex; mitochondrial outer membrane; mitochondrion; nucleus

Molecular Function: nucleotide binding; voltage-gated anion channel activity; porin activity

Biological Process: adenine transport; transmembrane transport; anion transport
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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