Rabbit Anti-ABCC4 Polyclonal Antibody – Cat# MBS3202467

WB Suggested Anti-ABCC4 Antibody
Titration: 1.0 ug/ml
Positive Control: 721_B Whole CellABCC4 is supported by BioGPS gene expression data to be expressed in 721_B

ABCC4 Antibody – Rabbit Polyclonal

Name: ABCC4 Antibody; Polyclonal; Rabbit; MyBioSource
Brand: MyBioSource
SKU: MBS3202467
Price: 490 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3202467

This is a rabbit polyclonal antibody against ABCC4. It was validated on Western BlotTarget Description: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across… More details

$490 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ABCC4, Polyclonal Antibody

Full Product Name

ABCC4 antibody - C-terminal region

Product Gene Name

anti-ABCC4 antibody

Product Synonym Gene Name

RP11-74A12.1; EST170205; MOAT-B; MOATB; MRP4

Immunogen Sequence

Synthetic peptide located within the following region: IAHRLNTIID SDKIMVLDSG RLKEYDEPYV LLQNKESLFY KMVQQLGKAE

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast

Form/Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Purity/Purification

Affinity Purified

Preparation and Storage

For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Antibody/Peptide Pairs

ABCC4 peptide (MBS3227445) is used for blocking the activity of ABCC4 antibody (MBS3202467)

Molecular Weight

98kDa

OMIM

605250

3D Structure

ModBase 3D Structure for O15439

Homology

Cow: 86%; Dog: 93%; Guinea Pig: 86%; Horse: 86%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 93%; Yeast: 79%

Product Categories/Family for anti-ABCC4 antibody

Polyclonal; Transcription Factor; Cancer; Transcription Regulation; Cell Biology; Developmental Biology; DNA/RNA/Protein Interactions

Applications Tested/Suitable for anti-ABCC4 antibody

Western Blot (WB)

Other Notes

Small volumes of anti-ABCC4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ABCC4 purchase

MBS3202467 is an antibody targeting ABCC4. Also known as ABCC4 antibody - C-terminal region. Reactive in Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ABCC4. It may not necessarily be applicable to this product.

NCBI GI #

3335175

NCBI GeneID

10257

NCBI Accession #

AAC27077

UniProt Primary Accession #

O15439

UniProt Related Accession #

O15439

GenBank Nucleotide #

NM_001105515

NCBI Official Full Name

ABC transporter MOAT-B isoform, partial

NCBI Official Synonym Full Names

ATP binding cassette subfamily C member 4

NCBI Official Symbol

ABCC4

NCBI Official Synonym Symbols

MRP4; MOATB; MOAT-B

UniProt Protein Name

Multidrug resistance-associated protein 4

UniProt Synonym Protein Names

ATP-binding cassette sub-family C member 4; MRP/cMOAT-related ABC transporter; Multi-specific organic anion transporter B; MOAT-B

Protein Family

ABC transporter C family

UniProt Gene Name

ABCC4

UniProt Synonym Gene Names

MRP4; MOAT-B

UniProt Entry Name

MRP4_HUMAN

NCBI Protein Information

multidrug resistance-associated protein 4

NCBI Summary for ABCC4

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This family member plays a role in cellular detoxification as a pump for its substrate, organic anions. It may also function in prostaglandin-mediated cAMP signaling in ciliogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]

UniProt Comments for ABCC4

ABCC4: a widely-expressed multi-pass membrane protein. An organic anion pump involved in cellular detoxification. Widely expressed, with particularly high levels in prostate, but is barely detectable in liver.

Protein type: Transporter; Membrane protein, multi-pass; Transporter, ABC family; Membrane protein, integral

Chromosomal Location of Human Ortholog: 13q32

Cellular Component: membrane; basolateral plasma membrane; integral to membrane; plasma membrane; platelet dense granule membrane

Molecular Function: ATPase activity, coupled to transmembrane movement of substances; 15-hydroxyprostaglandin dehydrogenase (NAD+) activity; ATP binding

Biological Process: response to drug; platelet activation; platelet degranulation; positive regulation of smooth muscle cell proliferation; response to organic nitrogen; blood coagulation; transmembrane transport; response to organic cyclic substance

Research Articles on ABCC4

1. Data show that forkhead box protein M1 (FoxM1) enhanced carboplatin resistance in Y-79CR cells through directly up-regulating the transcription of ATP-binding cassette transporter C4 (ABCC4).

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.