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CNOT3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3204435

This is a rabbit polyclonal antibody against CNOT3. It was validated on Western Blot using a cell lysate as a positive control.Target Description: CNOT3 is a protein component of CCR4-NOT protein complex. Yeast CCR4-NOT is a global regulator of RNA polymerase… More details

$490 / 0.1 mL +1 FREE 8GB USB
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
CNOT3, Polyclonal Antibody
Full Product Name
CNOT3 antibody - C terminal region
Product Gene Name
Product Synonym Gene Name
KIAA0691; LENG2; NOT3; NOT3H
Immunogen Sequence
Synthetic peptide located within the following region: MMWFQRHEEP KTITDEFEQG TYIYFDYEKW GQRKKEGFTF EYRYLEDRDL
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
CNOT3 peptide (MBS3229402) is used for blocking the activity of CNOT3 antibody (MBS3204435)
Molecular Weight
82kDa
OMIM
604910
3D Structure
ModBase 3D Structure for O75175
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human CNOT3
Applications Tested/Suitable for anti-CNOT3 antibody
Western Blot (WB)

Western Blot (WB) of anti-CNOT3 antibody

WB Suggested Anti-CNOT3 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: HT1080 cell lysate
Rabbit Anti-CNOT3 Polyclonal Antibody – Cat# MBS3204435

Other Notes

Small volumes of anti-CNOT3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CNOT3 purchase

MBS3204435 is an antibody targeting CNOT3. Also known as CNOT3 antibody - C terminal region. Reactive in Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CNOT3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
CCR4-NOT transcription complex subunit 3
NCBI Official Synonym Full Names
CCR4-NOT transcription complex subunit 3
NCBI Official Symbol
CNOT3
NCBI Official Synonym Symbols
NOT3; LENG2; NOT3H
UniProt Protein Name
CCR4-NOT transcription complex subunit 3
UniProt Synonym Protein Names
CCR4-associated factor 3; Leukocyte receptor cluster member 2
UniProt Gene Name
CNOT3
UniProt Synonym Gene Names
KIAA0691; LENG2; NOT3
UniProt Entry Name
CNOT3_HUMAN
NCBI Protein Information
CCR4-NOT transcription complex subunit 3

UniProt Comments for CNOT3

NOT3: The CCR4-NOT complex functions as general transcription regulation complex. Belongs to the CNOT2/3/5 family. 3 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 19q13.4

Cellular Component: nucleus; cytosol; CCR4-NOT complex

Molecular Function: protein binding

Biological Process: regulation of translation; poly(A) tail shortening; transcription, DNA-dependent; regulation of transcription, DNA-dependent; RNA-mediated gene silencing; gene expression; mRNA catabolic process, deadenylation-dependent decay; trophectodermal cell differentiation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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