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TRIM68 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3204559

This is a rabbit polyclonal antibody against TRIM68. It was validated on Western Blot using a cell lysate as a positive control.Target Description: The protein encoded by TRIM68 contains a RING finger domain, a motif present in a variety of functionally… More details

$490 / 0.1 mL +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
TRIM68, Polyclonal Antibody
Full Product Name
TRIM68 antibody - middle region
Product Gene Name
Product Synonym Gene Name
FLJ10369; MGC126176; RNF137; SS-56; SS56; GC109
Immunogen Sequence
Synthetic peptide located within the following region: VIRLRKGNEY RAGTDEYPIL SLPVPPRRVG IFVDYEAHDI SFYNVTDCGS
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat
Tested: Human
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Preparation and Storage
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
TRIM68 peptide (MBS3229526) is used for blocking the activity of TRIM68 antibody (MBS3204559)
Molecular Weight
56kDa
OMIM
613184
3D Structure
ModBase 3D Structure for Q6AZZ1
Protein Size
485 amino acids
Homology
Cow: 100%; Dog: 79%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 79%; Rat: 100%
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human TRIM68
Protein Interactions
NLRP1; TFG; VIM; UBC; HSP90B1; HNRNPL; BTN1A1; UBE2D3; UBE2U; KAT5; AR
Replacement Item
This antibody may replace item sc-130049 form Santa Cruz Biotechnology
Applications Tested/Suitable for anti-TRIM68 antibody
Immunohistochemistry (IHC), Western Blot (WB)

Immunohistochemistry (IHC) of anti-TRIM68 antibody

Immunohistochemistry with Human kidney lysate tissue at an antibody concentration of 5.0ug/ml using anti-TRIM68 antibody
Rabbit Anti-TRIM68 Polyclonal Antibody – Cat# MBS3204559

Western Blot (WB) of anti-TRIM68 antibody

Host: Rabbit
Target Name: TRIM68
Sample Type: Human Fetal Heart
Antibody Dilution: 1.0ug/ml
Rabbit Anti-TRIM68 Polyclonal Antibody, Western Blot (WB) – Cat# MBS3204559

Western Blot (WB) of anti-TRIM68 antibody

WB Suggested Anti-TRIM68 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: HepG2 cell lysate
Rabbit Anti-TRIM68 Polyclonal Antibody, Western Blot (WB) – Cat# MBS3204559

Other Notes

Small volumes of anti-TRIM68 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TRIM68 purchase

MBS3204559 is an antibody targeting TRIM68. Also known as TRIM68 antibody - middle region. Reactive in Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat
Tested: Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TRIM68. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
E3 ubiquitin-protein ligase TRIM68 isoform 1
NCBI Official Synonym Full Names
tripartite motif containing 68
NCBI Official Symbol
TRIM68
NCBI Official Synonym Symbols
SS56; GC109; SS-56; RNF137
UniProt Protein Name
E3 ubiquitin-protein ligase TRIM68
UniProt Synonym Protein Names
RING finger protein 137; SSA protein SS-56; SS-56; Tripartite motif-containing protein 68
UniProt Gene Name
TRIM68
UniProt Synonym Gene Names
GC109; RNF137; SS56; SS-56
UniProt Entry Name
TRI68_HUMAN
NCBI Protein Information
E3 ubiquitin-protein ligase TRIM68

NCBI Summary for TRIM68

This gene encodes a member of the tripartite motif-containing protein family, whose members are characterized by a "really interesting new gene" (RING) finger domain, a zinc-binding B-box motif, and a coiled-coil region. Members of this family function as E3 ubiquitin ligases and are involved in a broad range of biological processes. This gene regulates the activation of nuclear receptors, such as androgen receptor, and has been implicated in development of prostate cancer cells, where its expression increases in response to a downregulation of microRNAs. In addition, this gene participates in viral defense regulation as a negative regulator of interferon-beta. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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