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GRHL3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3204656

This is a rabbit polyclonal antibody against GRHL3. It was validated on Western Blot using a cell lysate as a positive control.Target Description: GRHL3 is a member of the grainyhead family of transcription factors. GRHL3 interacts with leader-binding protein… More details

$490 / 0.1 mL +1 FREE 8GB USB
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
GRHL3, Polyclonal Antibody
Full Product Name
GRHL3 antibody - C-terminal region
Product Gene Name
anti-GRHL3 antibody
Product Synonym Gene Name
SOM; TFCP2L4
Immunogen Sequence
Synthetic peptide located within the following region: EEVFDALMLK TPDLKGLRNA ISEKYGFPEE NIYKVYKKCK RGILVNMDNN
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
GRHL3 peptide (MBS3229623) is used for blocking the activity of GRHL3 antibody (MBS3204656)
Molecular Weight
57kDa
OMIM
608317
3D Structure
ModBase 3D Structure for Q8TE85
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 86%; Pig: 93%; Rabbit: 100%; Rat: 93%
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human GRHL3

Product Categories/Family for anti-GRHL3 antibody

Polyclonal; Signal Proteins; Transcription Regulation; Developmental Biology; DNA/RNA/Protein Interactions; Immunohistochemistry; Transcription Factors
Applications Tested/Suitable for anti-GRHL3 antibody
Immunohistochemistry (IHC), Western Blot (WB), Chromatin IP (ChIP)

Immunohistochemistry (IHC) of anti-GRHL3 antibody

Placenta
Rabbit Anti-GRHL3 Polyclonal Antibody – Cat# MBS3204656

Western Blot (WB) of anti-GRHL3 antibody

WB Suggested Anti-GRHL3 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: Jurkat cell lysate
Rabbit Anti-GRHL3 Polyclonal Antibody, Western Blot (WB) – Cat# MBS3204656

Other Notes

Small volumes of anti-GRHL3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GRHL3 purchase

MBS3204656 is an antibody targeting GRHL3. Also known as GRHL3 antibody - C-terminal region. Reactive in Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GRHL3. It may not necessarily be applicable to this product.

NCBI GI #
303324553
NCBI GeneID
57822
NCBI Accession #
NP_937817
UniProt Primary Accession #
Q8TE85
UniProt Related Accession #
Q8TE85
GenBank Nucleotide #
NM_198174
NCBI Official Full Name
grainyhead-like protein 3 homolog isoform 3
NCBI Official Synonym Full Names
grainyhead like transcription factor 3
NCBI Official Symbol
GRHL3
NCBI Official Synonym Symbols
SOM; VWS2; TFCP2L4
UniProt Protein Name
Grainyhead-like protein 3 homolog
UniProt Synonym Protein Names
Sister of mammalian grainyhead; Transcription factor CP2-like 4
Protein Family
Grainyhead-like protein
UniProt Gene Name
GRHL3
UniProt Synonym Gene Names
SOM; TFCP2L4
UniProt Entry Name
GRHL3_HUMAN
NCBI Protein Information
grainyhead-like protein 3 homolog

NCBI Summary for GRHL3

This gene encodes a member of the grainyhead family of transcription factors. The encoded protein may function as a transcription factor during development, and has been shown to stimulate migration of endothelial cells. Multiple transcript variants encoding distinct isoforms have been identified for this gene.[provided by RefSeq, Aug 2010]
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Research Articles on GRHL3

1. Non-melanoma skin cancer growth is accompanied by coordinated reduced expression of epidermal differentiation genes: GRHL1 and GRHL3, which may be regulated by miR-21-3p and -5p, respectively. Some potentially damaging single nucleotide polymorphisms in GRHL genes occur with altered frequencies in NMSC patients, and they may in particular impair the expression of GRHL3 gene or functioning of encoded protein
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GRHL3 antibody

 Reference Product  PubMed Publications
 TP63 antibody  >1 publications with GRHL3 and TP63

Diseases associated with anti-GRHL3 antibody

 Disease Name  Pubmed Publications
 Neural Tube Defects Antibodies  >11 publications with GRHL3 and Neural Tube Defects
 Carcinoma Antibodies  >6 publications with GRHL3 and Carcinoma
 Cell Transformation, Neoplastic Antibodies  >3 publications with GRHL3 and Cell Transformation, Neoplastic
 Breast Neoplasms Antibodies  >3 publications with GRHL3 and Breast Neoplasms
 Neoplasms, Experimental Antibodies  >2 publications with GRHL3 and Neoplasms, Experimental
 Hyperplasia Antibodies  >2 publications with GRHL3 and Hyperplasia
 Inflammation Antibodies  >2 publications with GRHL3 and Inflammation
 Embryo Loss Antibodies  >2 publications with GRHL3 and Embryo Loss
 Carcinoma, Hepatocellular Antibodies  >1 publications with GRHL3 and Carcinoma, Hepatocellular
 Eye Diseases Antibodies  >1 publications with GRHL3 and Eye Diseases

Organs/Tissues associated with anti-GRHL3 antibody

 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >27 publications with GRHL3 and Skin
 Embryonic Tissue Antibodies  >8 publications with GRHL3 and Embryonic Tissue
 Eye Antibodies  >3 publications with GRHL3 and Eye
 Lung Antibodies  >2 publications with GRHL3 and Lung
 Mouth Antibodies  >2 publications with GRHL3 and Mouth
 Mammary Gland Antibodies  >1 publications with GRHL3 and Mammary Gland
 Kidney Antibodies  >1 publications with GRHL3 and Kidney
 Thymus Antibodies  >1 publications with GRHL3 and Thymus
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