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GEMIN2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3205113

This is a rabbit polyclonal antibody against Sip1. It was validated on Western BlotTarget Description: The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. More details

$490 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Sip1 (GEMIN2), Polyclonal Antibody
Full Product Name
Sip1 antibody - N-terminal region
Product Gene Name
Product Synonym Gene Name
1700012N19Rik; Gemin2; Sip1
Immunogen Sequence
Synthetic peptide located within the following region: PRTPQEYLRR VQIEAAQCPD VVVAQIDPKK LKRKQSVNIS LSGCQPAPEG
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
Sip1 peptide (MBS3230078) is used for blocking the activity of Sip1 antibody (MBS3205113)
Molecular Weight
30kDa
3D Structure
ModBase 3D Structure for Q9CQQ4
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%
Immunogen
The immunogen is a synthetic peptide corresponding to a region of Mouse
Applications Tested/Suitable for anti-GEMIN2 antibody
Western Blot (WB)

Western Blot (WB) of anti-GEMIN2 antibody

WB Suggested Anti-Sip1 Antibody
Titration: 1.0 ug/ml
Positive Control: Mouse Brain
Rabbit Anti-GEMIN2 Polyclonal Antibody – Cat# MBS3205113

Other Notes

Small volumes of anti-GEMIN2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GEMIN2 purchase

MBS3205113 is an antibody targeting GEMIN2. Also known as Sip1 antibody - N-terminal region. Reactive in Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GEMIN2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
gem-associated protein 2
NCBI Official Synonym Full Names
gem nuclear organelle associated protein 2
NCBI Official Symbol
Gemin2
NCBI Official Synonym Symbols
Sip1; gemin-2
UniProt Protein Name
Gem-associated protein 2
UniProt Synonym Protein Names
Component of gems 2; Survival of motor neuron protein-interacting protein 1; SMN-interacting protein 1
UniProt Gene Name
Gemin2
UniProt Synonym Gene Names
Sip1; Gemin-2; SMN-interacting protein 1
UniProt Entry Name
GEMI2_MOUSE
NCBI Protein Information
gem-associated protein 2

NCBI Summary for GEMIN2

This gene encodes one of the proteins found in the survival of motor neuron (SMN) complex, which consists of the SMN protein and several gemin proteins. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal small nuclear ribonucleoproteins (snRNP) and for pre-mRNA splicing. This protein interacts directly with the SMN protein and it is required for formation of the SMN complex. Disruption of this gene in mouse resulted in impaired snRNP assembly, and motor neuron degeneration. [provided by RefSeq, Sep 2015]
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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