Rabbit Anti-ESRP2 Polyclonal Antibody – Cat# MBS3205600

WB Suggested Anti-RBM35B Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Hela cell lysateESRP2 is supported by BioGPS gene expression data to be expressed in HeLa

RBM35B (ESRP2) Antibody – Rabbit Polyclonal

Name: ESRP2 Antibody; Polyclonal; Rabbit; MyBioSource
Brand: MyBioSource
SKU: MBS3205600
Price: 490 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3205600

This is a rabbit polyclonal antibody against RBM35B. It was validated on Western Blot using a cell lysate as a positive control.Target Description: RBM35B contains 3 RRM (RNA recognition motif) domains. ESRP1 and ESRP2 (RBM35B) are epithelial… More details

$490 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

RBM35B (ESRP2), Polyclonal Antibody

Full Product Name

RBM35B antibody - N-terminal region

Product Gene Name

anti-ESRP2 antibody

Product Synonym Gene Name

FLJ21918; FLJ22248; RBM35B

Immunogen Sequence

Synthetic peptide located within the following region: ATAGALGRDL GSDETDLILL VWQVVEPRSR QVGTLHKSLV RAEAAALSTQ

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Cow, Dog, Guinea Pig, Human, Mouse, Rabbit, Rat

Form/Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Purity/Purification

Affinity Purified

Preparation and Storage

For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Antibody/Peptide Pairs

RBM35B peptide (MBS3230563) is used for blocking the activity of RBM35B antibody (MBS3205600)

Molecular Weight

77kDa

OMIM

612960

3D Structure

ModBase 3D Structure for Q9H6T0

Homology

Cow: 100%; Dog: 93%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human RBM35B

Product Categories/Family for anti-ESRP2 antibody

Polyclonal; RNA Binding Proteins

Applications Tested/Suitable for anti-ESRP2 antibody

Western Blot (WB)

Other Notes

Small volumes of anti-ESRP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ESRP2 purchase

MBS3205600 is an antibody targeting ESRP2. Also known as RBM35B antibody - N-terminal region. Reactive in Cow, Dog, Guinea Pig, Human, Mouse, Rabbit, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ESRP2. It may not necessarily be applicable to this product.

NCBI GI #

45935393

NCBI GeneID

80004

NCBI Accession #

NP_079215

UniProt Primary Accession #

Q9H6T0

UniProt Related Accession #

Q9H6T0

GenBank Nucleotide #

NM_024939

NCBI Official Full Name

epithelial splicing regulatory protein 2 isoform 1

NCBI Official Synonym Full Names

epithelial splicing regulatory protein 2

NCBI Official Symbol

ESRP2

NCBI Official Synonym Symbols

RBM35B

UniProt Protein Name

Epithelial splicing regulatory protein 2

UniProt Synonym Protein Names

RNA-binding motif protein 35B; RNA-binding protein 35B

Protein Family

Epithelial splicing regulatory protein

UniProt Gene Name

ESRP2

UniProt Synonym Gene Names

RBM35B

UniProt Entry Name

ESRP2_HUMAN

NCBI Protein Information

epithelial splicing regulatory protein 2

NCBI Summary for ESRP2

ESPR2 is an epithelial cell-type-specific splicing regulator (Warzecha et al., 2009 [PubMed 19285943]).[supplied by OMIM, Aug 2009]

UniProt Comments for ESRP2

RBM35B: mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2. Belongs to the ESRP family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding

Chromosomal Location of Human Ortholog: 16q22.1

Cellular Component: nucleoplasm; nucleus

Molecular Function: mRNA binding; nucleotide binding

Biological Process: regulation of RNA splicing; RNA splicing; mRNA processing

Research Articles on ESRP2

1. In conclusion, our findings suggested that IFNG-AS1 may function as an oncogene in pituitary adenoma by interacting with ESRP2.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ESRP2 antibody

Reference Product	PubMed Publications
FGFR2 antibody	>6 publications with ESRP2 and FGFR2
CD44 antibody	>4 publications with ESRP2 and CD44
CTNND1 antibody	>2 publications with ESRP2 and CTNND1
ENAH antibody	>2 publications with ESRP2 and ENAH
ST14 antibody	>1 publications with ESRP2 and ST14

Diseases associated with anti-ESRP2 antibody

Disease Name	Pubmed Publications
Breast Neoplasms Antibodies	>2 publications with ESRP2 and Breast Neoplasms
Skin Diseases Antibodies	>2 publications with ESRP2 and Skin Diseases
Lung Diseases Antibodies	>1 publications with ESRP2 and Lung Diseases

Organs/Tissues associated with anti-ESRP2 antibody

Organ/Tissue Name	Pubmed Publications
Lymph Antibodies	>2 publications with ESRP2 and Lymph
Lymph Node Antibodies	>2 publications with ESRP2 and Lymph Node
Nerve Antibodies	>1 publications with ESRP2 and Nerve
Connective Tissue Antibodies	>1 publications with ESRP2 and Connective Tissue
Prostate Antibodies	>1 publications with ESRP2 and Prostate
Placenta Antibodies	>1 publications with ESRP2 and Placenta
Skin Antibodies	>1 publications with ESRP2 and Skin
Brain Antibodies	>1 publications with ESRP2 and Brain
Lung Antibodies	>1 publications with ESRP2 and Lung