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SFRS2B (SRSF8) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3205613

This is a rabbit polyclonal antibody against SFRS2B. It was validated on Western Blot using a cell lysate as a positive control.Target Description: The SR (serine/arginine-rich) family contains a number of phosphoproteins that function as essential and… More details

$490 / 0.1 mL +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
SFRS2B (SRSF8), Polyclonal Antibody
Full Product Name
SFRS2B antibody - middle region
Product Gene Name
anti-SRSF8 antibody
Product Synonym Gene Name
SRP46; SFRS2B
Immunogen Sequence
Synthetic peptide located within the following region: YRESRYGGSH YSSSGYSNSR YSRYHSSRSH SKSGSSTSSR SASTSKSSSA
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
SFRS2B peptide (MBS3230576) is used for blocking the activity of SFRS2B antibody (MBS3205613)
Molecular Weight
32kDa
OMIM
603269
3D Structure
ModBase 3D Structure for Q9BRL6
Homology
Human: 100%
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human SFRS2B

Product Categories/Family for anti-SRSF8 antibody

Polyclonal; RNA Binding Proteins; Chromatin & Nuclear Signaling; DNA/RNA/Protein Interactions
Applications Tested/Suitable for anti-SRSF8 antibody
Immunohistochemistry (IHC), Western Blot (WB)

Immunohistochemistry (IHC) of anti-SRSF8 antibody

Rabbit Anti-SFRS2B antibody
Paraffin Embedded Tissue: Human Heart cell Cellular Data: cardiac cell of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X
Rabbit Anti-SRSF8 Polyclonal Antibody – Cat# MBS3205613

Immunohistochemistry (IHC) of anti-SRSF8 antibody

Rabbit Anti-SFRS2B antibody
Formalin Fixed Paraffin Embedded Tissue: Human Adult Prostate
Observed Staining: Cytoplasm in hepatocytes
Primary Antibody Concentration: 1:600
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec
Rabbit Anti-SRSF8 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS3205613

Western Blot (WB) of anti-SRSF8 antibody

WB Suggested Anti-SFRS2B Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: 721_B cell lysateSRSF8 is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells
Rabbit Anti-SRSF8 Polyclonal Antibody, Western Blot (WB) – Cat# MBS3205613

Other Notes

Small volumes of anti-SRSF8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SRSF8 purchase

MBS3205613 is an antibody targeting SRSF8. Also known as SFRS2B antibody - middle region. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SRSF8. It may not necessarily be applicable to this product.

NCBI GI #
15055543
NCBI GeneID
10929
NCBI Accession #
NP_115285
UniProt Primary Accession #
Q9BRL6
UniProt Related Accession #
Q9BRL6
GenBank Nucleotide #
NM_032102
NCBI Official Full Name
serine/arginine-rich splicing factor 8
NCBI Official Synonym Full Names
serine and arginine rich splicing factor 8
NCBI Official Symbol
SRSF8
NCBI Official Synonym Symbols
DSM-1; SRP46; SFRS2B
UniProt Protein Name
Serine/arginine-rich splicing factor 8
UniProt Synonym Protein Names
Pre-mRNA-splicing factor SRP46; Splicing factor SRp46; Splicing factor, arginine/serine-rich 2B
Protein Family
Serine/arginine-rich splicing factor
UniProt Gene Name
SRSF8
UniProt Synonym Gene Names
SFRS2B; SRP46; Splicing factor SRp46
UniProt Entry Name
SRSF8_HUMAN
NCBI Protein Information
serine/arginine-rich splicing factor 8

NCBI Summary for SRSF8

This gene encodes a member of a family of proteins containing a ribonucleoprotein (RNP)-type RNA binding motif and a carboxyl-terminal arginine-serine-rich (RS) domain. The encoded protein functions as a pre-mRNA splicing factor. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
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UniProt Comments for SRSF8

SRp46: Involved in pre-mRNA alternative splicing. Belongs to the splicing factor SR family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding

Chromosomal Location of Human Ortholog: 11q22

Cellular Component: nucleus

Molecular Function: protein binding; nucleotide binding

Biological Process: RNA splicing; mRNA processing
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-SRSF8 antibody

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