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NXF5 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3205624

This is a rabbit polyclonal antibody against NXF5. It was validated on Western BlotTarget Description: NXF5 is one member of a family of nuclear RNA export factors. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4… More details

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Product Overview

Online Datasheet in PDF
Product Name
NXF5, Polyclonal Antibody
Full Product Name
NXF5 antibody - C-terminal region
Product Gene Name
Immunogen Sequence
Synthetic peptide located within the following region: FTPVDFHYIR NRACFFVQVA SAASALKDVS YKIYDDENQK ICIFVSHFTA
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Cow, Dog, Human, Rabbit
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
NXF5 peptide (MBS3230587) is used for blocking the activity of NXF5 antibody (MBS3205624)
Molecular Weight
45kDa
OMIM
300319
3D Structure
ModBase 3D Structure for Q9H1B4
Homology
Cow: 86%; Dog: 86%; Human: 100%; Rabbit: 79%
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human NXF5
Applications Tested/Suitable for anti-NXF5 antibody
Western Blot (WB)

Western Blot (WB) of anti-NXF5 antibody

WB Suggested Anti-NXF5 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: COLO205 cell lysate
Rabbit Anti-NXF5 Polyclonal Antibody – Cat# MBS3205624

Other Notes

Small volumes of anti-NXF5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NXF5 purchase

MBS3205624 is an antibody targeting NXF5. Also known as NXF5 antibody - C-terminal region. Reactive in Cow, Dog, Human, Rabbit. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for NXF5. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
nuclear RNA export factor 5
NCBI Official Synonym Full Names
nuclear RNA export factor 5
NCBI Official Symbol
NXF5
UniProt Protein Name
Nuclear RNA export factor 5
UniProt Synonym Protein Names
TAP-like protein 1
UniProt Gene Name
NXF5
UniProt Synonym Gene Names
TAPL1; TAPL-1
UniProt Entry Name
NXF5_HUMAN
NCBI Protein Information
nuclear RNA export factor 5

NCBI Summary for NXF5

This gene is one member of a family of nuclear RNA export factor genes. The encoded protein can bind RNA, and is implicated in mRNA nuclear export. However, this protein has lost several C-terminal protein domains found in other family members that are required for export activity, and may be an evolving pseudogene. Alternatively spliced transcript variants have been described, but most are candidates for nonsense-mediated decay (NMD) and may not express proteins in vivo. [provided by RefSeq, Jul 2009]
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UniProt Comments for NXF5

NXF5: Could be involved in the export of mRNA from the nucleus to the cytoplasm. Could also have a role in polarized cytoplasmic transport and localization of mRNA in neurons. A chromosomal aberration involving NXF5 has been observed in one patient with a syndromic form of mental retardation and short stature. Pericentric inversion inv(X)(p21.1;q22) that interrupts NXF5. Belongs to the NXF family. 6 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: Xq22

Cellular Component: cytoplasm; nucleus

Molecular Function: protein binding; RNA binding; nucleotide binding

Biological Process: mRNA export from nucleus; multicellular organismal development; RNA transport
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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