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MSI2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3205653

This is a rabbit polyclonal antibody against MSI2. It was validated on Western Blot using a cell lysate as a positive control.Target Description: MSI2 contains two conserved tandem RNA recognition motifs. Similar proteins in other species function as… More details

$490 / 0.1 mL +1 FREE 8GB USB
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
MSI2, Polyclonal Antibody
Full Product Name
MSI2 antibody - N-terminal region
Product Gene Name
Product Synonym Gene Name
FLJ36569; MGC3245; MSI2H
Immunogen Sequence
Synthetic peptide located within the following region: EANGSQGTSG SANDSQHDPG KMFIGGLSWQ TSPDSLRDYF SKFGEIRECM
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Pig, Rabbit, Rat, Zebrafish
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
MSI2 peptide (MBS3230617) is used for blocking the activity of MSI2 antibody (MBS3205653)
Molecular Weight
35kDa
OMIM
607897
3D Structure
ModBase 3D Structure for Q96DH6
Homology
Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human MSI2
Applications Tested/Suitable for anti-MSI2 antibody
Western Blot (WB)

Western Blot (WB) of anti-MSI2 antibody

MSI2 antibody - N-terminal region validated by WB using K562 cells lysate at 1:1000.
Rabbit Anti-MSI2 Polyclonal Antibody – Cat# MBS3205653

Western Blot (WB) of anti-MSI2 antibody

WB Suggested Anti-MSI2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: Hela cell lysate
Rabbit Anti-MSI2 Polyclonal Antibody, Western Blot (WB) – Cat# MBS3205653

Other Notes

Small volumes of anti-MSI2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MSI2 purchase

MBS3205653 is an antibody targeting MSI2. Also known as MSI2 antibody - N-terminal region. Reactive in Human, Mouse, Pig, Rabbit, Rat, Zebrafish. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MSI2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
RNA-binding protein Musashi homolog 2 isoform a
NCBI Official Synonym Full Names
musashi RNA binding protein 2
NCBI Official Symbol
MSI2
NCBI Official Synonym Symbols
MSI2H
UniProt Protein Name
RNA-binding protein Musashi homolog 2
Protein Family
UniProt Gene Name
MSI2
UniProt Synonym Gene Names
Musashi-2
UniProt Entry Name
MSI2H_HUMAN
NCBI Protein Information
RNA-binding protein Musashi homolog 2

NCBI Summary for MSI2

This gene encodes an RNA-binding protein that is a member of the Musashi protein family. The encoded protein is transcriptional regulator that targets genes involved in development and cell cycle regulation. Mutations in this gene are associated with poor prognosis in certain types of cancers. This gene has also been shown to be rearranged in certain cancer cells. [provided by RefSeq, Apr 2016]
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UniProt Comments for MSI2

Musashi-2: RNA binding protein that regulates the expression of target mRNAs at the translation level. May play a role in the proliferation and maintenance of stem cells in the central nervous system. Chromosomal aberrations involving MSI2 may contribute to disease progression in chronic myeloid leukemia. Translocation t(7;17)(p15;q23) with HOXA9; translocation t(7;17)(q32-34;q23). Belongs to the Musashi family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding

Chromosomal Location of Human Ortholog: 17q22

Cellular Component: polysome; cytoplasm

Molecular Function: nucleotide binding; poly(U) binding

Biological Process: stem cell development
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-MSI2 antibody

Pathways associated with anti-MSI2 antibody

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