Rabbit Anti-BTRC Polyclonal Antibody – Cat# MBS3206223

WB Suggested Anti-Btrc Antibody
Titration: 1.0 ug/ml
Positive Control: Mouse Pancreas

BTRC Antibody – Rabbit Polyclonal

Name: BTRC Antibody; Polyclonal; Rabbit; MyBioSource
Brand: MyBioSource
SKU: MBS3206223
Price: 490 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3206223

This is a rabbit polyclonal antibody against Btrc. It was validated on Western BlotTarget Description: Btrc is a substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and… More details

$490 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Btrc, Polyclonal Antibody

Full Product Name

Btrc antibody - C-terminal region

Product Gene Name

anti-BTRC antibody

Product Synonym Gene Name

Beta-Trcp1; FWD1; Fbw1a; KIAA4123; Slimb; b-TrCP; beta-TrCP; mKIAA4123; HOS

Immunogen Sequence

Synthetic peptide located within the following region: LVEHSGRVFR LQFDEFQIVS SSHDDTILIW DFLNDPAAHA EPPRSPSRTY

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat

Form/Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Purity/Purification

Affinity Purified

Preparation and Storage

For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Antibody/Peptide Pairs

Btrc peptide (MBS3231188) is used for blocking the activity of Btrc antibody (MBS3206223)

Molecular Weight

69kDa

3D Structure

ModBase 3D Structure for Q3ULA2

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 86%

Product Categories/Family for anti-BTRC antibody

Polyclonal; Transcription Regulation; Transcription Regulation; Phosphorylation; Transcription Factors

Applications Tested/Suitable for anti-BTRC antibody

Western Blot (WB)

Other Notes

Small volumes of anti-BTRC antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BTRC purchase

MBS3206223 is an antibody targeting BTRC. Also known as Btrc antibody - C-terminal region. Reactive in Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for BTRC. It may not necessarily be applicable to this product.

NCBI GI #

161086887

NCBI GeneID

12234

NCBI Accession #

NP_001032847

UniProt Primary Accession #

Q3ULA2

UniProt Related Accession #

Q3ULA2

GenBank Nucleotide #

NM_001037758

NCBI Official Full Name

F-box/WD repeat-containing protein 1A isoform a

NCBI Official Synonym Full Names

beta-transducin repeat containing protein

NCBI Official Symbol

Btrc

NCBI Official Synonym Symbols

HOS; FWD1; Fbw1a; Slimb; b-TrCP; beta-TrCP; Beta-Trcp1; SCF b-TRCP; E3RSIkappaB; E3RS-IkappaB

UniProt Protein Name

F-box/WD repeat-containing protein 1A

UniProt Synonym Protein Names

Beta-TrCP protein E3RS-IkappaB; Beta-transducin repeat-containing protein; Beta-TrCP; E3RSIkappaB; mE3RS-IkappaB; F-box and WD repeats protein beta-TrCP; HOS; Ubiquitin ligase FWD1; pIkappaB-E3 receptor subunit

Protein Family

F-box/WD repeat-containing protein

UniProt Gene Name

Btrc

UniProt Synonym Gene Names

Fbw1; Fbxw1; Fwd1; Kiaa4123; Beta-TrCP; mE3RS-IkappaB

UniProt Entry Name

FBW1A_MOUSE

NCBI Protein Information

F-box/WD repeat-containing protein 1A

Research Articles on BTRC

1. beta-TrCP was identified as a novel interacting partner of ASK1 that is capable of ubiquitinating and degrading ASK1 through the ubiquitin-proteasome system. These findings suggest that beta-TrCP is capable of suppressing oxidative stress-induced caspase 3-dependent apoptosis through suppression of ASK1.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-BTRC antibody

Products by Pathway	Pathway Diagram
APC/C-mediated Degradation Of Cell Cycle Proteins Pathway antibodies	APC/C-mediated Degradation Of Cell Cycle Proteins Pathway Diagram
Cell Cycle Pathway antibodies	Cell Cycle Pathway Diagram
Cell Cycle, Mitotic Pathway antibodies	Cell Cycle, Mitotic Pathway Diagram
Circadian Clock Pathway antibodies	Circadian Clock Pathway Diagram
Circadian Rhythm - Mammal Pathway antibodies	Circadian Rhythm - Mammal Pathway Diagram
Circadian Rhythm - Mammal Pathway antibodies	Circadian Rhythm - Mammal Pathway Diagram
Degradation Of Beta-catenin By The Destruction Complex Pathway antibodies	Degradation Of Beta-catenin By The Destruction Complex Pathway Diagram
Hedgehog Signaling Pathway antibodies	Hedgehog Signaling Pathway Diagram
Hedgehog Signaling Pathway antibodies	Hedgehog Signaling Pathway Diagram
Oocyte Meiosis Pathway antibodies	Oocyte Meiosis Pathway Diagram

Diseases associated with anti-BTRC antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>25 publications with BTRC and Neoplasms
Nervous System Diseases Antibodies	>6 publications with BTRC and Nervous System Diseases
Congenital Abnormalities Antibodies	>4 publications with BTRC and Congenital Abnormalities
Genetic Predisposition to Disease Antibodies	>3 publications with BTRC and Genetic Predisposition to Disease
Genomic Instability Antibodies	>2 publications with BTRC and Genomic Instability
Cardiovascular Diseases Antibodies	>2 publications with BTRC and Cardiovascular Diseases
Fibrosis Antibodies	>1 publications with BTRC and Fibrosis
Neural Tube Defects Antibodies	>1 publications with BTRC and Neural Tube Defects
Abnormalities, Multiple Antibodies	>1 publications with BTRC and Abnormalities, Multiple
Death Antibodies	>1 publications with BTRC and Death