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ARPP21 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3206392

This is a rabbit polyclonal antibody against ARPP-21. It was validated on Western Blot using a cell lysate as a positive control.Target Description: This gene encodes a cAMP-regulated phosphoprotein. The encoded protein is enriched in the caudate nucleus and… More details

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Product Overview

Online Datasheet in PDF
Product Name
ARPP21, Polyclonal Antibody
Full Product Name
ARPP21 Antibody - N-terminal region
Product Gene Name
Product Synonym Gene Name
RCS; TARPP; R3HDM3; ARPP-21
Immunogen Sequence
Synthetic peptide located within the following region: ESSARPGGES LQDQESIHLQ LSSFSSLQEE DKSRKDDSER EKEKDKNKDK
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Yeast
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
ARPP21 peptide (MBS3231358) is used for blocking the activity of ARPP21 antibody (MBS3206392)
Molecular Weight
89kDa
OMIM
605488
3D Structure
ModBase 3D Structure for Q9UBL0
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Yeast: 82%
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human ARPP-21

Product Categories/Family for anti-ARPP21 antibody

Applications Tested/Suitable for anti-ARPP21 antibody
Western Blot (WB)

Western Blot (WB) of anti-ARPP21 antibody

Host: Rabbit
Target Name: ARPP-21
Sample Type: Human Fetal Brain
Antibody Dilution: 1.0ug/ml
Rabbit Anti-ARPP21 Polyclonal Antibody – Cat# MBS3206392

Western Blot (WB) of anti-ARPP21 antibody

WB Suggested Anti-ARPP-21 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Human brain
Rabbit Anti-ARPP21 Polyclonal Antibody, Western Blot (WB) – Cat# MBS3206392

Other Notes

Small volumes of anti-ARPP21 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ARPP21 purchase

MBS3206392 is an antibody targeting ARPP21. Also known as ARPP21 Antibody - N-terminal region. Reactive in Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Yeast. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ARPP21. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
cAMP-regulated phosphoprotein 21 isoform 1
NCBI Official Synonym Full Names
cAMP regulated phosphoprotein 21
NCBI Official Symbol
ARPP21
NCBI Official Synonym Symbols
RCS; TARPP; R3HDM3; ARPP-21
UniProt Protein Name
cAMP-regulated phosphoprotein 21
UniProt Synonym Protein Names
Thymocyte cAMP-regulated phosphoprotein
UniProt Gene Name
ARPP21
UniProt Synonym Gene Names
TARPP; ARPP-21
UniProt Entry Name
ARP21_HUMAN
NCBI Protein Information
cAMP-regulated phosphoprotein 21

NCBI Summary for ARPP21

This gene encodes a cAMP-regulated phosphoprotein. The encoded protein is enriched in the caudate nucleus and cerebellar cortex. A similar protein in mouse may be involved in regulating the effects of dopamine in the basal ganglia. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]
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UniProt Comments for ARPP21

ARPP-21: a cytosolic neuronal phosphoprotein highly enriched in the striatum and in other dopamine-innervated regions of the brain. Phosphorylated in a c-AMP dependent fashion.

Protein type: Inhibitor

Chromosomal Location of Human Ortholog: 3p22.3

Cellular Component: cytoplasm

Molecular Function: calmodulin binding; nucleic acid binding
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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