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SLC22A7 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3206519

This is a rabbit polyclonal antibody against SLC22A7. It was validated on Western Blot and immunohistochemistryTarget Description: SLC22A7 is involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic.… More details

$490 / 0.1 mL +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
SLC22A7, Polyclonal Antibody
Full Product Name
SLC22A7 antibody - C-terminal region
Product Gene Name
Product Synonym Gene Name
MGC24091; MGC45202; NLT; OAT2
Immunogen Sequence
Synthetic peptide located within the following region: LSLPKLTYGG IALLAAGTAL LLPETRQAQL PETIQDVERK SAPTSLQEEE
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
SLC22A7 peptide (MBS3231483) is used for blocking the activity of SLC22A7 antibody (MBS3206519)
Molecular Weight
26kDa
OMIM
604995
3D Structure
ModBase 3D Structure for Q9Y694
Homology
Cow: 93%; Dog: 91%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 93%; Rabbit: 100%; Rat: 100%
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human SLC22A7
Applications Tested/Suitable for anti-SLC22A7 antibody
Immunohistochemistry (IHC), Western Blot (WB)

Immunohistochemistry (IHC) of anti-SLC22A7 antibody

Human kidney
Rabbit Anti-SLC22A7 Polyclonal Antibody – Cat# MBS3206519

Western Blot (WB) of anti-SLC22A7 antibody

WB Suggested Anti-SLC22A7 Antibody Titration: 0.2-1 ug/ml
Positive Control: Jurkat cell lysateThere is BioGPS gene expression data showing that SLC22A7 is expressed in Jurkat
Rabbit Anti-SLC22A7 Polyclonal Antibody, Western Blot (WB) – Cat# MBS3206519

Other Notes

Small volumes of anti-SLC22A7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SLC22A7 purchase

MBS3206519 is an antibody targeting SLC22A7. Also known as SLC22A7 antibody - C-terminal region. Reactive in Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SLC22A7. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
Solute carrier family 22 member 7
NCBI Official Synonym Full Names
solute carrier family 22 member 7
NCBI Official Symbol
SLC22A7
NCBI Official Synonym Symbols
NLT; OAT2; hOAT11
UniProt Protein Name
Solute carrier family 22 member 7
UniProt Synonym Protein Names
Novel liver transporter; Organic anion transporter 2; hOAT2
Protein Family
UniProt Gene Name
SLC22A7
UniProt Synonym Gene Names
NLT; OAT2; hOAT2
UniProt Entry Name
S22A7_HUMAN
NCBI Protein Information
solute carrier family 22 member 7

NCBI Summary for SLC22A7

The protein encoded by this gene is involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and appears to be localized to the basolateral membrane of the kidney. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
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UniProt Comments for SLC22A7

SLC22A7: Mediates sodium-independent multispecific organic anion transport. Transport of prostaglandin E2, prostaglandin F2, tetracycline, bumetanide, estrone sulfate, glutarate, dehydroepiandrosterone sulfate, allopurinol, 5-fluorouracil, paclitaxel, L-ascorbic acid, salicylate, ethotrexate, and alpha- ketoglutarate. Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; Transporter, SLC family; Transporter

Chromosomal Location of Human Ortholog: 6p21.1

Cellular Component: membrane; basolateral plasma membrane; integral to plasma membrane; plasma membrane

Molecular Function: sodium-independent organic anion transmembrane transporter activity

Biological Process: transmembrane transport; organic anion transport
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Research Articles on SLC22A7

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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