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HERC3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3206778

This is a rabbit polyclonal antibody against HERC3. It was validated on Western BlotTarget Description: This gene encodes a member the HERC ubiquitin ligase family. The encoded protein is located in the cytosol and binds ubiquitin via a HECT domain. Mutations… More details

$490 / 0.1 mL +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
HERC3, Polyclonal Antibody
Full Product Name
HERC3 Antibody - middle region
Product Gene Name
Immunogen Sequence
Synthetic peptide located within the following region: LHFPLALYKK LLNVKPGLED LKELSPTEGR SLQELLDYPG EDVEETFCLN
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
HERC3 peptide (MBS3231743) is used for blocking the activity of HERC3 antibody (MBS3206778)
Molecular Weight
54kDa
OMIM
D25215 mRNA
3D Structure
ModBase 3D Structure for Q15034
Homology
Cow: 92%; Dog: 100%; Guinea Pig: 100%; Horse: 92%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 91%; Zebrafish: 85%
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human HERC3

Product Categories/Family for anti-HERC3 antibody

Applications Tested/Suitable for anti-HERC3 antibody
Western Blot (WB)

Western Blot (WB) of anti-HERC3 antibody

Host: Rabbit
Target Name: HERC3
Sample Type: ACHN Whole Cell lysates
Antibody Dilution: 1.0ug/ml
Rabbit Anti-HERC3 Polyclonal Antibody – Cat# MBS3206778

Other Notes

Small volumes of anti-HERC3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HERC3 purchase

MBS3206778 is an antibody targeting HERC3. Also known as HERC3 Antibody - middle region. Reactive in Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for HERC3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
probable E3 ubiquitin-protein ligase HERC3 isoform 2
NCBI Official Synonym Full Names
HECT and RLD domain containing E3 ubiquitin protein ligase 3
NCBI Official Symbol
HERC3
UniProt Protein Name
Probable E3 ubiquitin-protein ligase HERC3
UniProt Synonym Protein Names
HECT domain and RCC1-like domain-containing protein 3; HECT-type E3 ubiquitin transferase HERC3
UniProt Gene Name
HERC3
UniProt Synonym Gene Names
KIAA0032
NCBI Protein Information
probable E3 ubiquitin-protein ligase HERC3

NCBI Summary for HERC3

This gene encodes a member the HERC ubiquitin ligase family. The encoded protein is located in the cytosol and binds ubiquitin via a HECT domain. Mutations in this gene have been associated with colorectal and gastric carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2012]
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UniProt Comments for HERC3

HERC3: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

Protein type: EC 6.3.2.-; EC 6.3.2.19; Ligase; Ubiquitin conjugating system; Ubiquitin ligase

Chromosomal Location of Human Ortholog: 4q22.1

Cellular Component: cytoplasm; cytoplasmic vesicle; cytosol

Biological Process: protein ubiquitination
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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