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LETMD1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3207513

This is a rabbit polyclonal antibody against LETMD1. It was validated on Western Blot using a cell lysate as a positive control.Target Description: LETMD1 is involved in tumorigenesis and may function as a negative regulator of the TP53/p53. More details

$490 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
LETMD1, Polyclonal Antibody
Full Product Name
LETMD1 antibody - middle region
Product Gene Name
Product Synonym Gene Name
1110019O13Rik; DKFZp586A011; HCCR-2; HCCR1; HCCR-1; HCRR-2
Immunogen Sequence
Synthetic peptide located within the following region: LLRHRLKTHT TVIHQLDKAL AKLGIGQLTA QEVKSACYLR GLNSTHIGED
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
LETMD1 peptide (MBS3232478) is used for blocking the activity of LETMD1 antibody (MBS3207513)
Molecular Weight
36kDa
3D Structure
ModBase 3D Structure for Q6P1Q0
Homology
Cow: 93%; Dog: 86%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 92%
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human LETMD1
Applications Tested/Suitable for anti-LETMD1 antibody
Western Blot (WB)

Immunohistochemistry (IHC) of anti-LETMD1 antibody

Rabbit Anti-LETMD1 antibody
Formalin Fixed Paraffin Embedded Tissue: Human Kidney
Primary antibody Concentration: 1:100
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20x
Exposure Time: 0.5-2.0sec
Rabbit Anti-LETMD1 Polyclonal Antibody – Cat# MBS3207513

Immunohistochemistry (IHC) of anti-LETMD1 antibody

Rabbit Anti-LETMD1 antibody
Formalin Fixed Paraffin Embedded Tissue: Human Skin
Primary antibody Concentration: 1:100
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20x
Exposure Time: 0.5-2.0sec
Rabbit Anti-LETMD1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS3207513

Western Blot (WB) of anti-LETMD1 antibody

WB Suggested Anti-LETMD1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: PANC1 cell lysate
Rabbit Anti-LETMD1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS3207513

Other Notes

Small volumes of anti-LETMD1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LETMD1 purchase

MBS3207513 is an antibody targeting LETMD1. Also known as LETMD1 antibody - middle region. Reactive in Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for LETMD1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Synonym Full Names
LETM1 domain containing 1
NCBI Official Symbol
LETMD1
NCBI Official Synonym Symbols
HCCR; HCCR1; HCCR2; HCCR-1; HCCR-2; HCRR-2; SLC55A3; 1110019O13Rik
UniProt Protein Name
LETM1 domain-containing protein 1
UniProt Synonym Protein Names
Cervical cancer 1 proto-oncogene protein p40; Cervical cancer proto-oncogene 2 protein; HCCR-1; HCRR-2
UniProt Gene Name
LETMD1
UniProt Entry Name
LTMD1_HUMAN
NCBI Protein Information
LETM1 domain-containing protein 1

NCBI Summary for LETMD1

This gene encodes a mitochondrial outer membrane protein. It has a potential role in tumorigenesis, which may result from negative regulation of the p53 tumor suppressor gene. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Aug 2011]

UniProt Comments for LETMD1

LETMD1: Involved in tumorigenesis and may function as a negative regulator of the p53/TP53. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: Oncoprotein; Membrane protein, integral

Chromosomal Location of Human Ortholog: 12q13.12

Cellular Component: mitochondrial outer membrane; integral to membrane

Molecular Function: protein binding
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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