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GZMK Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3207689

This is a rabbit polyclonal antibody against GZMK. It was validated on Western Blot using a cell lysate as a positive control.Target Description: GZMK is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes.… More details

$490 / 0.1 mL +1 FREE 8GB USB
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
GZMK, Polyclonal Antibody
Full Product Name
GZMK antibody - N-terminal region
Product Gene Name
Product Synonym Gene Name
TRYP2
Immunogen Sequence
Synthetic peptide located within the following region: PTVVLGAHSL SKNEASKQTL EIKKFIPFSR VTSDPQSNDI MLVKLQTAAK
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Horse, Human, Pig
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
GZMK peptide (MBS3232655) is used for blocking the activity of GZMK antibody (MBS3207689)
Molecular Weight
26kDa
OMIM
600784
3D Structure
ModBase 3D Structure for P49863
Homology
Horse: 79%; Human: 100%; Pig: 86%
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human GZMK
Applications Tested/Suitable for anti-GZMK antibody
Western Blot (WB)

Western Blot (WB) of anti-GZMK antibody

WB Suggested Anti-GZMK Antibody Titration: 0.2-1 ug/ml
Positive Control: HepG2 cell lysate
Rabbit Anti-GZMK Polyclonal Antibody – Cat# MBS3207689

Other Notes

Small volumes of anti-GZMK antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GZMK purchase

MBS3207689 is an antibody targeting GZMK. Also known as GZMK antibody - N-terminal region. Reactive in Horse, Human, Pig. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GZMK. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
granzyme K
NCBI Official Synonym Full Names
granzyme K
NCBI Official Symbol
GZMK
NCBI Official Synonym Symbols
TRYP2
UniProt Protein Name
Granzyme K
UniProt Synonym Protein Names
Fragmentin-3; Granzyme-3; NK-tryptase-2
Protein Family
UniProt Gene Name
GZMK
UniProt Synonym Gene Names
TRYP2; NK-Tryp-2
UniProt Entry Name
GRAK_HUMAN
NCBI Protein Information
granzyme K

NCBI Summary for GZMK

This gene product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes. [provided by RefSeq, Jul 2008]
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UniProt Comments for GZMK

GZMK: this protein is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes. [provided by RefSeq, Jul 2008]

Protein type: EC 3.4.21.-; Protease; Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 5q11.2

Cellular Component: extracellular region

Molecular Function: serine-type peptidase activity; serine-type endopeptidase activity

Biological Process: proteolysis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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