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JAG2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3207698

The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch protein family are transmembrane receptors that are critical for various cell fate decisions. JAG2 is one of several… More details

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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
JAG2, Polyclonal Antibody
Full Product Name
JAG2 antibody - N-terminal region
Product Gene Name
Product Synonym Gene Name
HJ2; SER2
Immunogen Sequence
RAQGRGRLPR RLLLLLALWV QAARPMGYFE LQLSALRNVN GELLSGACCD
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Tested Reactivity: Human
Predicted Reactivity: Human, Mouse, Pig, Rat
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Concentration
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml (lot specific)
Preparation and Storage
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
JAG2 peptide (MBS3232664) is used for blocking the activity of JAG2 antibody (MBS3207698)
Molecular Weight
130kDa
3D Structure
ModBase 3D Structure for Q9Y219
Protein Size (# AA)
1238 amino acids
Protein Interactions
GFI1B; ATN1; ATXN7; CACNA1A; MIB2; NOTCH3; NOTCH2; NOTCH1;
Blocking Peptide
For anti-JAG2 (MBS3207698) antibody is Catalog # MBS3232664
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human JAG2
Replacement Item
This antibody may replace item sc-8157 from Santa Cruz Biotechnology.
Predicted Homology
Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%
Applications Tested/Suitable for anti-JAG2 antibody
Western Blot (WB), Immunohistochemistry (IHC)

Immunohistochemistry (IHC) of anti-JAG2 antibody

JAG2 antibody - N-terminal region

Formalin Fixed Paraffin Embedded Tissue: Human Bronchial Epithelial Tissue

Observed Staining: Membrane of bronchial epithelial tissue

Primary Antibody Concentration: 1:100

Secondary Antibody: Donkey anti-Rabbit-Cy3

Secondary Antibody Concentration: 1:200

Magnification: 20X

Exposure Time: 0.5 - 2.0 sec
Rabbit Anti-JAG2 Polyclonal Antibody – Cat# MBS3207698

Western Blot (WB) of anti-JAG2 antibody

WB Suggested Anti-JAG2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Jurkat cell lysate
Rabbit Anti-JAG2 Polyclonal Antibody, Western Blot (WB) – Cat# MBS3207698

Other Notes

Small volumes of anti-JAG2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for JAG2 purchase

MBS3207698 is an antibody targeting JAG2. Also known as JAG2 antibody - N-terminal region. Reactive in Tested Reactivity: Human
Predicted Reactivity: Human, Mouse, Pig, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for JAG2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
protein jagged-2 isoform a
NCBI Official Synonym Full Names
jagged canonical Notch ligand 2
NCBI Official Symbol
JAG2
NCBI Official Synonym Symbols
HJ2; SER2
UniProt Protein Name
Protein jagged-2
Protein Family
UniProt Gene Name
JAG2
UniProt Synonym Gene Names
Jagged2; hJ2
NCBI Protein Information
protein jagged-2

NCBI Summary for JAG2

The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. The protein encoded by this gene is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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UniProt Comments for JAG2

Putative Notch ligand involved in the mediation of Notch signaling. Involved in limb development ().

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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