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LBR Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3207700

This is a rabbit polyclonal antibody against LBR. It was validated on Western Blot using a cell lysate as a positive control.Target Description: The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner… More details

$490 / 0.1 mL +1 FREE 8GB USB
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
LBR, Polyclonal Antibody
Full Product Name
LBR antibody - middle region
Product Gene Name
Product Synonym Gene Name
DHCR14B; LMN2R; MGC9041; PHA
Immunogen Sequence
Synthetic peptide located within the following region: GANSQKNAFR KNPSDPKLAH LKTIHTSTGK NLLVSGWWGF VRHPNYLGDL
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Yeast, Zebrafish
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
LBR peptide (MBS3232666) is used for blocking the activity of LBR antibody (MBS3207700)
Molecular Weight
71kDa
OMIM
L25931 mRNA
3D Structure
ModBase 3D Structure for Q14739
Homology
Cow: 86%; Dog: 93%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 93%; Pig: 93%; Rabbit: 93%; Rat: 100%; Yeast: 77%; Zebrafish: 79%
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human LBR
Applications Tested/Suitable for anti-LBR antibody
Western Blot (WB)

Western Blot (WB) of anti-LBR antibody

WB Suggested Anti-LBR Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: RPMI 8226 cell lysateLBR is supported by BioGPS gene expression data to be expressed in RPMI 8226
Rabbit Anti-LBR Polyclonal Antibody – Cat# MBS3207700

Other Notes

Small volumes of anti-LBR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LBR purchase

MBS3207700 is an antibody targeting LBR. Also known as LBR antibody - middle region. Reactive in Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Yeast, Zebrafish. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for LBR. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
delta(14)-sterol reductase
NCBI Official Synonym Full Names
lamin B receptor
NCBI Official Symbol
LBR
NCBI Official Synonym Symbols
PHA; C14SR; LMN2R; PHASK; TDRD18; DHCR14B
UniProt Protein Name
Lamin-B receptor
UniProt Synonym Protein Names
Integral nuclear envelope inner membrane protein; LMN2R
Protein Family
UniProt Gene Name
LBR
NCBI Protein Information
delta(14)-sterol reductase; lamin-B receptor

NCBI Summary for LBR

The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
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UniProt Comments for LBR

Anchors the lamina and the heterochromatin to the inner nuclear membrane.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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