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TMPRSS4 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3209466

This is a rabbit polyclonal antibody against TMPRSS4. It was validated on Western BlotTarget Description: This gene encodes a member of the serine protease family. Serine proteases are known to be involved in a variety of biological processes, whose… More details

$490 / 0.1 mL +1 FREE 8GB USB
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
TMPRSS4, Polyclonal Antibody
Full Product Name
TMPRSS4 antibody - N-terminal region
Product Gene Name
Product Synonym Gene Name
MT-SP2; TMPRSS3; CAPH2
Immunogen Sequence
Synthetic peptide located within the following region: IPRKQLCDGE LDCPLGEDEE HCVKSFPEGP AVAVRLSKDR STLQVLDSAT
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
TMPRSS4 peptide (MBS3234425) is used for blocking the activity of TMPRSS4 antibody (MBS3209466)
Molecular Weight
48kDa
OMIM
606565
3D Structure
ModBase 3D Structure for Q9NRS4
Homology
Cow: 85%; Dog: 92%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 85%; Rat: 100%
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human TMPRSS4
Applications Tested/Suitable for anti-TMPRSS4 antibody
Western Blot (WB)

Western Blot (WB) of anti-TMPRSS4 antibody

WB Suggested Anti-TMPRSS4 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: Jurkat cell lysate
Rabbit Anti-TMPRSS4 Polyclonal Antibody – Cat# MBS3209466

Other Notes

Small volumes of anti-TMPRSS4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TMPRSS4 purchase

MBS3209466 is an antibody targeting TMPRSS4. Also known as TMPRSS4 antibody - N-terminal region. Reactive in Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TMPRSS4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
transmembrane protease serine 4 isoform 3
NCBI Official Synonym Full Names
transmembrane serine protease 4
NCBI Official Symbol
TMPRSS4
NCBI Official Synonym Symbols
CAPH2; MT-SP2; TMPRSS3
UniProt Protein Name
Transmembrane protease serine 4
UniProt Synonym Protein Names
Channel-activating protease 2; CAPH2; Membrane-type serine protease 2; MT-SP2
UniProt Gene Name
TMPRSS4
UniProt Synonym Gene Names
TMPRSS3; CAPH2; MT-SP2
UniProt Entry Name
TMPS4_HUMAN
NCBI Protein Information
transmembrane protease serine 4

NCBI Summary for TMPRSS4

This gene encodes a member of the serine protease family. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified as a gene overexpressed in pancreatic carcinoma. The encoded protein is membrane bound with a N-terminal anchor sequence and a glycosylated extracellular region containing the serine protease domain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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UniProt Comments for TMPRSS4

TMPRSS4: Probable protease. Seems to be capable of activating ENaC. Belongs to the peptidase S1 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.4.21.-; Protease; Membrane protein, integral

Chromosomal Location of Human Ortholog: 11q23.3

Cellular Component: integral to membrane

Molecular Function: serine-type endopeptidase activity; scavenger receptor activity

Biological Process: receptor-mediated endocytosis; proteolysis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-TMPRSS4 antibody

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