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SLITRK1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3209840

This is a rabbit polyclonal antibody against SLITRK1. It was validated on Western Blot using a cell lysate as a positive control.Target Description: Members of the SLITRK family, such as SLITRK1, are integral membrane proteins with 2 N-terminal leucine-rich… More details

$490 / 0.1 mL +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
SLITRK1, Polyclonal Antibody
Full Product Name
SLITRK1 antibody - N-terminal region
Product Gene Name
Product Synonym Gene Name
KIAA0918; KIAA1910; LRRC12; RP11-395N17.1; TTM
Immunogen Sequence
Synthetic peptide located within the following region: CDLLSLKEWL ENIPKNALIG RVVCEAPTRL QGKDLNETTE QDLCPLKNRV
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
SLITRK1 peptide (MBS3234795) is used for blocking the activity of SLITRK1 antibody (MBS3209840)
Molecular Weight
78kDa
OMIM
gene 613229
3D Structure
ModBase 3D Structure for Q96PX8
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 85%
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human SLITRK1
Applications Tested/Suitable for anti-SLITRK1 antibody
Western Blot (WB)

Western Blot (WB) of anti-SLITRK1 antibody

WB Suggested Anti-SLITRK1 Antibody Titration: 0.2-1 ug/ml
Positive Control: Human Lung
Rabbit Anti-SLITRK1 Polyclonal Antibody – Cat# MBS3209840

Other Notes

Small volumes of anti-SLITRK1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SLITRK1 purchase

MBS3209840 is an antibody targeting SLITRK1. Also known as SLITRK1 antibody - N-terminal region. Reactive in Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SLITRK1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
SLIT and NTRK-like protein 1
NCBI Official Synonym Full Names
SLIT and NTRK like family member 1
NCBI Official Symbol
SLITRK1
NCBI Official Synonym Symbols
TTM; LRRC12
UniProt Protein Name
SLIT and NTRK-like protein 1
UniProt Synonym Protein Names
Leucine-rich repeat-containing protein 12
UniProt Gene Name
SLITRK1
UniProt Synonym Gene Names
KIAA1910; LRRC12
UniProt Entry Name
SLIK1_HUMAN
NCBI Protein Information
SLIT and NTRK-like protein 1

NCBI Summary for SLITRK1

This gene encodes a member of the SLITRK protein family. Members of this family are integral membrane proteins that are characterized by two N-terminal leucine-rich repeat (LRR) domains and a C-terminal region that shares homology with trk neurotrophin receptors. However, the protein encoded by this gene lacks the region of homology to neurotrophin receptors. This protein is thought to be involved in neurite outgrowth. Mutations in this gene may be associated with Tourette syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
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UniProt Comments for SLITRK1

SLITRK1: Enhances neuronal dendrite outgrowth. Defects in SLITRK1 may be a cause of Gilles de la Tourette syndrome (GTS). GTS is a neurologic disorder manifested particularly by motor and vocal tics and associated with behavioral abnormalities. Defects in SLITRK1 may be a cause of trichotillomania (TTM). It is a neuropsychiatric disorder characterized by chronic, repetitive, or compulsive hair pulling resulting in noticeable hair loss. Affected individuals may develop physical complications and often have overlapping psychologic disorders, such as Gilles de la Tourette syndrome or obsessive-compulsive disorder. Belongs to the SLITRK family.

Protein type: Membrane protein, integral; Cell development/differentiation

Chromosomal Location of Human Ortholog: 13q31.1

Cellular Component: integral to membrane

Biological Process: axonogenesis; homeostatic process; multicellular organism growth; adult behavior

Disease: Gilles De La Tourette Syndrome; Trichotillomania
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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