Rabbit Anti-ANKH Polyclonal Antibody – Cat# MBS3209852

WB Suggested Anti-ANKH Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: THP-1 cell lysate

ANKH Antibody – Rabbit Polyclonal

Name: ANKH Antibody; Polyclonal; Rabbit; MyBioSource
Brand: MyBioSource
SKU: MBS3209852
Price: 490 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3209852

This is a rabbit polyclonal antibody against ANKH. It was validated on Western Blot using a cell lysate as a positive control.Target Description: ANKH regulates intra- and extracellular levels of inorganic pyrophosphate (PPi), probably functioning as PPi… More details

$490 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ANKH, Polyclonal Antibody

Full Product Name

ANKH antibody - N-terminal region

Product Gene Name

anti-ANKH antibody

Product Synonym Gene Name

ANK; CCAL2; CMDJ; CPPDD; FLJ27166; HANK; MANK

Immunogen Sequence

Synthetic peptide located within the following region: SDLGYYIINK LHHVDESVGS KTRRAFLYLA AFPFMDAMAW THAGILLKHK

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish

Form/Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Purity/Purification

Affinity Purified

Preparation and Storage

For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Antibody/Peptide Pairs

ANKH peptide (MBS3234807) is used for blocking the activity of ANKH antibody (MBS3209852)

Molecular Weight

54kDa

OMIM

605145

3D Structure

ModBase 3D Structure for Q9HCJ1

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human ANKH

Product Categories/Family for anti-ANKH antibody

Polyclonal; Membrane Protein; Disease Related

Applications Tested/Suitable for anti-ANKH antibody

Western Blot (WB)

Other Notes

Small volumes of anti-ANKH antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ANKH purchase

MBS3209852 is an antibody targeting ANKH. Also known as ANKH antibody - N-terminal region. Reactive in Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ANKH. It may not necessarily be applicable to this product.

NCBI GI #

16905507

NCBI GeneID

56172

NCBI Accession #

NP_473368

UniProt Primary Accession #

Q9HCJ1

UniProt Related Accession #

Q9HCJ1

GenBank Nucleotide #

NM_054027

NCBI Official Full Name

progressive ankylosis protein homolog

NCBI Official Synonym Full Names

ANKH inorganic pyrophosphate transport regulator

NCBI Official Symbol

ANKH

NCBI Official Synonym Symbols

ANK; CMDJ; HANK; MANK; CCAL2; CPPDD; SLC62A1

UniProt Protein Name

Progressive ankylosis protein homolog

Protein Family

Progressive ankylosis protein

UniProt Gene Name

ANKH

UniProt Synonym Gene Names

KIAA1581; UNQ241/PRO274; ANK

UniProt Entry Name

ANKH_HUMAN

NCBI Protein Information

progressive ankylosis protein homolog

NCBI Summary for ANKH

This gene encodes a multipass transmembrane protein that is expressed in joints and other tissues and controls pyrophosphate levels in cultured cells. Progressive ankylosis-mediated control of pyrophosphate levels has been suggested as a possible mechanism regulating tissue calcification and susceptibility to arthritis in higher animals. Mutations in this gene have been associated with autosomal dominant craniometaphyseal dysplasia. [provided by RefSeq, Jul 2008]

Research Articles on ANKH

1. Craniometaphyseal dysplasia mutations in ANKH diminish hiPSC differentiation into osteoclasts in vitro.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-ANKH antibody

Disease Name	Pubmed Publications
Chondrocalcinosis Antibodies	>35 publications with ANKH and Chondrocalcinosis
Calcium Metabolism Disorders Antibodies	>14 publications with ANKH and Calcium Metabolism Disorders
Disease Models, Animal Antibodies	>9 publications with ANKH and Disease Models, Animal
Craniofacial Abnormalities Antibodies	>8 publications with ANKH and Craniofacial Abnormalities
Inflammation Antibodies	>6 publications with ANKH and Inflammation
Vascular Calcification Antibodies	>5 publications with ANKH and Vascular Calcification
Neoplasms Antibodies	>4 publications with ANKH and Neoplasms
Hypertension Antibodies	>2 publications with ANKH and Hypertension
Fibrosis Antibodies	>2 publications with ANKH and Fibrosis
Tooth Abnormalities Antibodies	>2 publications with ANKH and Tooth Abnormalities

Organs/Tissues associated with anti-ANKH antibody

Organ/Tissue Name	Pubmed Publications
Bone Antibodies	>41 publications with ANKH and Bone
Connective Tissue Antibodies	>11 publications with ANKH and Connective Tissue
Blood Antibodies	>8 publications with ANKH and Blood
Muscle Antibodies	>5 publications with ANKH and Muscle
Kidney Antibodies	>5 publications with ANKH and Kidney
Parathyroid Antibodies	>4 publications with ANKH and Parathyroid
Nerve Antibodies	>4 publications with ANKH and Nerve
Brain Antibodies	>4 publications with ANKH and Brain
Liver Antibodies	>2 publications with ANKH and Liver
Embryonic Tissue Antibodies	>2 publications with ANKH and Embryonic Tissue