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HMX2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3209966

This is a rabbit polyclonal antibody against HMX2. It was validated on Western Blot using a cell lysate as a positive control.Target Description: HMX2 belongs to the HMX homeobox family. It contains 1 homeobox DNA-binding domain. HMX2 is a transcription… More details

$490 / 0.1 mL +1 FREE 8GB USB
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
HMX2, Polyclonal Antibody
Full Product Name
HMX2 antibody - middle region
Product Gene Name
Product Synonym Gene Name
H6L; Nkx5-2
Immunogen Sequence
Synthetic peptide located within the following region: SPSHSDFKEE KERLLPAGSP SPGSERPRDG GAERQAGAAK KKTRTVFSRS
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
HMX2 peptide (MBS3234921) is used for blocking the activity of HMX2 antibody (MBS3209966)
Molecular Weight
29kDa
OMIM
600647
3D Structure
ModBase 3D Structure for A2RU54
Homology
Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human HMX2
Applications Tested/Suitable for anti-HMX2 antibody
Western Blot (WB)

Western Blot (WB) of anti-HMX2 antibody

WB Suggested Anti-HMX2 Antibody Titration: 0.2-1 ug/ml
Positive Control: Human brain
Rabbit Anti-HMX2 Polyclonal Antibody – Cat# MBS3209966

Other Notes

Small volumes of anti-HMX2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HMX2 purchase

MBS3209966 is an antibody targeting HMX2. Also known as HMX2 antibody - middle region. Reactive in Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for HMX2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
homeobox protein HMX2
NCBI Official Synonym Full Names
H6 family homeobox 2
NCBI Official Symbol
HMX2
NCBI Official Synonym Symbols
H6L; Nkx5-2
UniProt Protein Name
Homeobox protein HMX2
UniProt Synonym Protein Names
Homeobox protein H6 family member 2
Protein Family
UniProt Gene Name
HMX2
UniProt Entry Name
HMX2_HUMAN
NCBI Protein Information
homeobox protein HMX2

NCBI Summary for HMX2

The protein encoded by this gene is a member of the NKL homeobox family of transcription factors. Members in this family are of ancient origin and play an important role in organ development during embryogenesis. A related mouse protein plays a role in patterning of inner ear structures. In humans, variations in a region containing this gene have been associated with inner ear malformations, vestibular dysfunction, and hearing loss. [provided by RefSeq, Aug 2012]
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UniProt Comments for HMX2

HMX2: Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. Belongs to the HMX homeobox family.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 10q26.13

Cellular Component: nucleus

Molecular Function: sequence-specific DNA binding

Biological Process: positive regulation of nuclear mRNA splicing, via spliceosome; inner ear morphogenesis; transcription, DNA-dependent; regulation of transcription, DNA-dependent; positive regulation of cell proliferation; brain development; cell differentiation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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