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DCP1B Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3210107

This is a rabbit polyclonal antibody against DCP1B. It was validated on Western Blot using a cell lysate as a positive control.Target Description: DCP1B may play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA… More details

$490 / 0.1 mL +1 FREE 8GB USB
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
DCP1B, Polyclonal Antibody
Full Product Name
DCP1B antibody - N-terminal region
Product Gene Name
Product Synonym Gene Name
DCP1; hDcp1b
Immunogen Sequence
Synthetic peptide located within the following region: TLDPEPQHLS LTALFGKQDK ATCQETVEPP QTLHQQQQQQ QQQQEKLPIR
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
DCP1B peptide (MBS3235062) is used for blocking the activity of DCP1B antibody (MBS3210107)
Molecular Weight
68kDa
OMIM
609843
3D Structure
ModBase 3D Structure for Q8IZD4
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 93%; Rabbit: 100%; Rat: 93%
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human DCP1B
Applications Tested/Suitable for anti-DCP1B antibody
Western Blot (WB)

Western Blot (WB) of anti-DCP1B antibody

WB Suggested Anti-DCP1B Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: 721_B cell lysate
Rabbit Anti-DCP1B Polyclonal Antibody – Cat# MBS3210107

Other Notes

Small volumes of anti-DCP1B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DCP1B purchase

MBS3210107 is an antibody targeting DCP1B. Also known as DCP1B antibody - N-terminal region. Reactive in Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for DCP1B. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
mRNA-decapping enzyme 1B isoform 1
NCBI Official Synonym Full Names
decapping mRNA 1B
NCBI Official Symbol
DCP1B
NCBI Official Synonym Symbols
DCP1
UniProt Protein Name
mRNA-decapping enzyme 1B
Protein Family
UniProt Gene Name
DCP1B
UniProt Entry Name
DCP1B_HUMAN
NCBI Protein Information
mRNA-decapping enzyme 1B

NCBI Summary for DCP1B

This gene encodes a member of a family of proteins that function in removing the 5' cap from mRNAs, which is a step in regulated mRNA decay. This protein localizes to cytoplasmic foci which are the site of mRNA breakdown and turnover. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
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UniProt Comments for DCP1B

DCP1B: an mRNA decapping enzyme. Plays a role in regulating the mRNA degradation pathway.

Protein type: RNA-binding; EC 3.-.-.-; Hydrolase

Chromosomal Location of Human Ortholog: 12p13.33

Cellular Component: intracellular membrane-bound organelle; membrane; cytoplasm; nucleus; cytosol

Molecular Function: mRNA binding; protein binding; hydrolase activity; RNA 7-methylguanosine cap binding; enzyme regulator activity

Biological Process: deadenylation-dependent decapping; regulation of catalytic activity; deadenylation-independent decapping; mRNA catabolic process, nonsense-mediated decay; gene expression; mRNA catabolic process, deadenylation-dependent decay
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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