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AP3S1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3210515

This is a rabbit polyclonal antibody against AP3S1. It was validated on Western Blot using a cell lysate as a positive control.Target Description: AP3S1 is part of the AP-3 complex, an adapter-related complex which is not clathrin-associated. The complex is… More details

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Product Overview

Online Datasheet in PDF
Product Name
AP3S1, Polyclonal Antibody
Full Product Name
AP3S1 antibody - N-terminal region
Product Gene Name
Product Synonym Gene Name
CLAPS3; Sigma3A
Immunogen Sequence
Synthetic peptide located within the following region: IKAILIFNNH GKPRLSKFYQ PYSEDTQQQI IRETFHLVSK RDENVCNFLE
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Cow, Dog, Guinea Pig, Human, Mouse, Rabbit, Rat
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
AP3S1 peptide (MBS3235470) is used for blocking the activity of AP3S1 antibody (MBS3210515)
Molecular Weight
22kDa
OMIM
601507
3D Structure
ModBase 3D Structure for Q92572
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human AP3S1

Product Categories/Family for anti-AP3S1 antibody

Applications Tested/Suitable for anti-AP3S1 antibody
Western Blot (WB)

Western Blot (WB) of anti-AP3S1 antibody

WB Suggested Anti-AP3S1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Jurkat cell lysate
Rabbit Anti-AP3S1 Polyclonal Antibody – Cat# MBS3210515

Other Notes

Small volumes of anti-AP3S1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AP3S1 purchase

MBS3210515 is an antibody targeting AP3S1. Also known as AP3S1 antibody - N-terminal region. Reactive in Cow, Dog, Guinea Pig, Human, Mouse, Rabbit, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for AP3S1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
AP-3 complex subunit sigma-1 isoform 1
NCBI Official Synonym Full Names
adaptor related protein complex 3 subunit sigma 1
NCBI Official Symbol
AP3S1
NCBI Official Synonym Symbols
CLAPS3; Sigma3A
UniProt Protein Name
AP-3 complex subunit sigma-1
UniProt Synonym Protein Names
AP-3 complex subunit sigma-3A; Adaptor-related protein complex 3 subunit sigma-1; Clathrin-associated/assembly/adaptor protein, small 3; Sigma-3A-adaptin; Sigma3A-adaptin; Sigma-adaptin 3a
Protein Family
UniProt Gene Name
AP3S1
UniProt Synonym Gene Names
CLAPS3; Sigma3A-adaptin
UniProt Entry Name
AP3S1_HUMAN
NCBI Protein Information
AP-3 complex subunit sigma-1

NCBI Summary for AP3S1

This gene encodes a subunit of the AP3 adaptor complex. This complex functions in the formation of subcellular vesicles budded from the Golgi body. Several related pseudogenes of this gene have been found. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
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UniProt Comments for AP3S1

AP3S1: Part of the AP-3 complex, an adapter-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. Belongs to the adaptor complexes small subunit family.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 5q22

Cellular Component: Golgi apparatus; transport vesicle; cytoplasmic vesicle membrane; AP-type membrane coat adaptor complex

Molecular Function: protein binding; transporter activity; protein transporter activity

Biological Process: intracellular protein transport; anterograde synaptic vesicle transport; insulin receptor signaling pathway; anterograde axon cargo transport
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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