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PPM1K Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3211096

This is a rabbit polyclonal antibody against PPM1K. It was validated on Western Blot using a cell lysate as a positive control.Target Description: PPM1K regulates the mitochondrial permeability transition pore and is essential for cellular survival and… More details

$490 / 0.1 mL +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
PPM1K, Polyclonal Antibody
Full Product Name
PPM1K antibody - middle region
Product Gene Name
Product Synonym Gene Name
DKFZp667B084; DKFZp761G058; PP2Cm; PTMP; UG0882E07; hPTMP; PP2Ckappa
Immunogen Sequence
Synthetic peptide located within the following region: AHAVTEQAIQ YGTEDNSTAV VVPFGAWGKY KNSEINFSFS RSFASSGRWA
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
PPM1K peptide (MBS3236049) is used for blocking the activity of PPM1K antibody (MBS3211096)
Molecular Weight
41kDa
OMIM
611065
3D Structure
ModBase 3D Structure for Q8N3J5
Homology
Cow: 93%; Dog: 92%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 85%
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human PPM1K
Applications Tested/Suitable for anti-PPM1K antibody
Western Blot (WB)

Western Blot (WB) of anti-PPM1K antibody

WB Suggested Anti-PPM1K Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Human Placenta
Rabbit Anti-PPM1K Polyclonal Antibody – Cat# MBS3211096

Other Notes

Small volumes of anti-PPM1K antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PPM1K purchase

MBS3211096 is an antibody targeting PPM1K. Also known as PPM1K antibody - middle region. Reactive in Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PPM1K. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
protein phosphatase 1K, mitochondrial
NCBI Official Synonym Full Names
protein phosphatase, Mg2+/Mn2+ dependent 1K
NCBI Official Symbol
PPM1K
NCBI Official Synonym Symbols
BDP; PTMP; PP2Cm; MSUDMV; PP2Ckappa; UG0882E07
UniProt Protein Name
Protein phosphatase 1K, mitochondrial
UniProt Synonym Protein Names
PP2C domain-containing protein phosphatase 1K; PP2C-like mitochondrial protein; PP2C-type mitochondrial phosphoprotein phosphatase; PTMP; Protein phosphatase 2C isoform kappa
Protein Family
UniProt Gene Name
PPM1K
UniProt Synonym Gene Names
PP2CM; PTMP; PP2C-kappa
UniProt Entry Name
PPM1K_HUMAN
NCBI Protein Information
protein phosphatase 1K, mitochondrial

NCBI Summary for PPM1K

This gene encodes a member of the PPM family of Mn2+/Mg2+-dependent protein phosphatases. The encoded protein, essential for cell survival and development, is targeted to the mitochondria where it plays a key role in regulation of the mitochondrial permeability transition pore. [provided by RefSeq, Sep 2012]
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UniProt Comments for PPM1K

PPM1K: Regulates the mitochondrial permeability transition pore and is essential for cellular survival and development. Belongs to the PP2C family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Mitochondrial; Motility/polarity/chemotaxis; EC 3.1.3.16; Protein phosphatase, Ser/Thr (non-receptor)

Chromosomal Location of Human Ortholog: 4q22.1

Cellular Component: mitochondrial matrix

Molecular Function: metal ion binding; protein serine/threonine phosphatase activity

Biological Process: protein amino acid dephosphorylation

Disease: Maple Syrup Urine Disease, Mild Variant
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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