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RDH10 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3211199

This is a rabbit polyclonal antibody against RDH10. It was validated on Western Blot using a cell lysate as a positive control.Target Description: RDH10 is a retinol dehydrogenase with a clear preference for NADP. RDH10 converts all-trans-retinol to… More details

$490 / 0.1 mL +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
RDH10, Polyclonal Antibody
Full Product Name
RDH10 antibody - N-terminal region
Product Gene Name
Product Synonym Gene Name
SDR16C4
Immunogen Sequence
Synthetic peptide located within the following region: QSNEETAGMV RHIYRDLEAA DAAALQAGNG EEEILPHCNL QVFTYTCDVG
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
RDH10 peptide (MBS3236151) is used for blocking the activity of RDH10 antibody (MBS3211199)
Molecular Weight
38kDa
OMIM
607599
3D Structure
ModBase 3D Structure for Q8IZV5
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human RDH10
Applications Tested/Suitable for anti-RDH10 antibody
Western Blot (WB)

Western Blot (WB) of anti-RDH10 antibody

WB Suggested Anti-RDH10 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Human heart
Rabbit Anti-RDH10 Polyclonal Antibody – Cat# MBS3211199

Other Notes

Small volumes of anti-RDH10 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RDH10 purchase

MBS3211199 is an antibody targeting RDH10. Also known as RDH10 antibody - N-terminal region. Reactive in Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for RDH10. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
retinol dehydrogenase 10
NCBI Official Synonym Full Names
retinol dehydrogenase 10
NCBI Official Symbol
RDH10
NCBI Official Synonym Symbols
SDR16C4
UniProt Protein Name
Retinol dehydrogenase 10
Protein Family
UniProt Gene Name
RDH10
UniProt Entry Name
RDH10_HUMAN
NCBI Protein Information
retinol dehydrogenase 10

NCBI Summary for RDH10

This gene encodes a retinol dehydrogenase, which converts all-trans-retinol to all-trans-retinal, with preference for NADP as a cofactor. Studies in mice suggest that this protein is essential for synthesis of embryonic retinoic acid and is required for limb, craniofacial, and organ development. [provided by RefSeq, Dec 2011]
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UniProt Comments for RDH10

Function: Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinol to all-trans-retinal. Has no detectable activity towards 11-cis-retinol, 9-cis-retinol and 13-cis-retinol. Ref.1

Catalytic activity: All-trans-retinol + NADP+ = all-trans-retinal + NADPH. Ref.1

Pathway: Cofactor metabolism; retinol metabolism.

Subcellular location: Microsome membrane; Single-pass membrane protein

Potential. Endoplasmic reticulum membrane; Single-pass membrane protein

Potential Ref.1.

Tissue specificity: Detected in retina, kidney, liver, small intestine, placenta, lung, heart and skeletal muscle. Ref.1 Ref.4

Sequence similarities: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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